Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8184837 | 0.88 | SLC6A4 (0.37) | HTR1ATSHRHTR2ASLC6A4DRD2 | |
| SCHEMBL8175851 | 0.85 | KAT2B (0.33) | HTR1AHTR2ASLC6A4DRD2KAT2B | |
| SCHEMBL8804858 | 0.85 | CYP2D6 (0.36) | HTR1AKDM4ECYP2D6MAPTTSHR | |
| SCHEMBL8177078 | 0.85 | ADRA1A (0.35) | HTR1AHTR2CHTR2ASLC6A4DRD2 | |
| SCHEMBL9138352 | 0.84 | BACE1 (0.37) | HTR1AKDM4ECYP2D6MAPTTSHR | |
| SCHEMBL8186216 | 0.83 | SLC6A4 (0.36) | CYP2D6CYP3A4SLC6A4KCNH2KAT2B | |
| SCHEMBL9139815 | 0.81 | PTGS2 (0.34) | MAPTKAT2BPTGS2TP53 | |
| SCHEMBL8804355 | 0.81 | ADRA1A (0.47) | HTR1AKDM4ECYP2D6MAPTTSHR | |
| SCHEMBL9138413 | 0.81 | DRD3 (0.40) | DRD2KCNH2 | |
| SCHEMBL8803343 | 0.80 | CYP2D6 (0.51) | HTR1AKDM4ECYP2D6MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475105-A | N-substituted azabicycloheptane derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |