Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 7/20 | 0.40 |
| ▸ | DRD2 | P14416 | 6/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804858 | 0.90 | CYP2D6 (0.36) | DRD3DRD2KCNH2CHRM1CHRM3 | |
| SCHEMBL9139815 | 0.88 | PTGS2 (0.34) | ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL8806161 | 0.85 | GRIA2 (0.33) | DRD3DRD2KCNH2 | |
| SCHEMBL8186216 | 0.84 | SLC6A4 (0.36) | KCNH2 | |
| SCHEMBL9138352 | 0.83 | BACE1 (0.37) | DRD3DRD2KCNH2CHRM1CHRM3 | |
| SCHEMBL7014109 | 0.82 | ADRA2A (0.32) | ADRA2AADRA2BADRA2C | |
| SCHEMBL8804674 | 0.81 | CARM1 (0.34) | DRD3DRD2KCNH2DRD4ADRA2A | |
| SCHEMBL9142476 | 0.81 | MAPT (0.47) | DRD3DRD2DRD4ADRA2AADRA2B | |
| SCHEMBL9139885 | 0.81 | HTR1A (0.33) | DRD2KCNH2 | |
| SCHEMBL8878777 | 0.80 | MAPT (0.35) | DRD3DRD2KCNH2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475105-A | N-substituted azabicycloheptane derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |