Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | HTR6 | P50406 | 3/20 | 0.33 |
| ▸ | HTR7 | P34969 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804674 | 0.89 | CARM1 (0.34) | KCNH2CARM1PRMT6ACHEHTR2C | |
| SCHEMBL8804858 | 0.89 | CYP2D6 (0.36) | KCNH2ACHEHTR6HTR7HTR1A | |
| SCHEMBL8186216 | 0.86 | SLC6A4 (0.36) | KCNH2CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9139885 | 0.84 | HTR1A (0.33) | KCNH2ACHEHTR1ACYP2D6TSHR | |
| SCHEMBL9139815 | 0.83 | PTGS2 (0.34) | ADRA2AADRA2BADRA2CADRA1AMAPT | |
| SCHEMBL7014109 | 0.83 | ADRA2A (0.32) | ADRA2AADRA2BADRA2CCYP3A4 | |
| SCHEMBL9138413 | 0.83 | DRD3 (0.40) | KCNH2DRD2ADRA2ACHRM1ADRA2B | |
| SCHEMBL8804087 | 0.81 | TSHR (0.35) | KCNH2ACHEHTR6HTR7HTR1A | |
| SCHEMBL8184837 | 0.81 | SLC6A4 (0.37) | HTR1ATSHRDRD2HTR2AADRA2A | |
| SCHEMBL8806161 | 0.81 | GRIA2 (0.33) | KCNH2HTR7DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475105-A | N-substituted azabicycloheptane derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |