Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621358 | 0.78 | TACR3 (0.34) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL8075796 | 0.75 | GFER (0.46) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL11750861 | 0.72 | EGLN1 (0.35) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL10544974 | 0.70 | LMNA (0.47) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL8082564 | 0.69 | MEN1 (0.49) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL11812036 | 0.69 | MMP12 (0.50) | ALDH1A1KDM4EKMT2AHPGDROCK2 | |
| SCHEMBL17706538 | 0.69 | ALDH1A1 (0.52) | ALDH1A1KDM4EKMT2AHPGDROCK2 | |
| SCHEMBL18163749 | 0.69 | KDM4E (0.53) | ALDH1A1KDM4EKMT2AHPGDROCK2 | |
| SCHEMBL9795277 | 0.68 | HPGDS (0.49) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL15713099 | 0.68 | KDM4E (0.52) | ALDH1A1KDM4EKMT2AHPGDROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363223-A2 | 3-Aryloxymethyl-cephalosporin derivatives, their preparation and their medical use | Sankyo Company Limited (JP) | 1990-04-11 | — | — | EP | claimed |
| US-5389626-A | 3-aryloxmethyl-cephalosporin derivatives, and their medical use | SANKYO COMPANY, LIMITED (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0363223-A2 | 3-Aryloxymethyl-cephalosporin derivatives, their preparation and their medical use | Sankyo Company Limited (JP) | 1990-04-11 | — | — | EP | disclosed |