Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4471126 | 0.86 | MCL1 (0.62) | MCL1ALDH1A1KMT2AMEN1HDAC8 | |
| SCHEMBL7107935 | 0.84 | ALDH1A1 (0.77) | ALDH1A1KMT2AMEN1HDAC8HDAC6 | |
| SCHEMBL9563921 | 0.79 | ALDH1A1 (0.75) | ALDH1A1KMT2AMEN1HDAC8HDAC6 | |
| SCHEMBL19277778 | 0.78 | MCL1 (0.69) | MCL1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL1529438 | 0.77 | MCL1 (0.55) | MCL1ALDH1A1KMT2AMEN1HDAC8 | |
| SCHEMBL29148895 | 0.77 | MEN1 (0.72) | ALDH1A1KMT2AMEN1HDAC8HDAC6 | |
| SCHEMBL654148 | 0.76 | MCL1 (1.00) | MCL1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL12389341 | 0.76 | ALOX5 (0.56) | MCL1ALDH1A1KDM4EGAALMNA | |
| SCHEMBL10612693 | 0.76 | CTSS (0.66) | MCL1ALDH1A1KMT2AMEN1HDAC8 | |
| SCHEMBL8370299 | 0.76 | MCL1 (0.58) | MCL1ALDH1A1KDM4EEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466812-A | Reacting alkyl cyanoacetate with hydrazine; catalysis, phase transfer; lactamization, cyclization | BASF AKTIENGESELLSCHAFT (DE) | 1995-11-14 | — | — | US | disclosed |
| EP-0413226-B1 | [1,2,4]Triazo [1,5-a]pyridine | BASF AG (DE) | 1995-05-24 | — | — | EP | disclosed |
| EP-0628547-A1 | Process for the preparation of N-aminopyridones | BASF Aktiengesellschaft (DE) | 1994-12-14 | — | — | EP | disclosed |
| EP-0413226-A2 | [1,2,4]Triazo [1,5-a]pyridine | BASF Aktiengesellschaft (DE) | 1991-02-20 | — | — | EP | disclosed |