Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 12/20 | 0.38 |
| ▸ | DRD2 | P14416 | 12/20 | 0.38 |
| ▸ | HTR2A | P28223 | 12/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9136776 | 0.91 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAHTR1ADRD2 | |
| SCHEMBL8803940 | 0.91 | KCNH2 (0.40) | ALDH1A1MAPTLMNAHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9247876 | 0.91 | KCNH2 (0.39) | ALDH1A1MAPTLMNAHTR1ADRD2 | |
| SCHEMBL8803818 | 0.90 | HTR2A (0.38) | ALDH1A1MAPTHTR1ADRD2HTR2A | |
| SCHEMBL9139219 | 0.90 | HTR1A (0.37) | ALDH1A1MAPTLMNAHTR1ADRD2 | |
| SCHEMBL9137947 | 0.90 | ALDH1A1 (0.46) | ALDH1A1MAPTHTR1ADRD2HTR2A | |
| SCHEMBL8805764 | 0.86 | KCNH2 (0.37) | ALDH1A1MAPTLMNAHTR1ADRD2 | |
| SCHEMBL8803882 | 0.84 | USP2 (0.35) | HTR1ADRD2HTR2AHTR2CADRA1A | |
| SCHEMBL8805519 | 0.78 | TDP1 (0.52) | ALDH1A1MAPTLMNAHTR1ADRD2 | |
| SCHEMBL9142928 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAXDHCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475105-A | N-substituted azabicycloheptane derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |