Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 15/20 | 0.38 |
| ▸ | HTR1A | P08908 | 14/20 | 0.38 |
| ▸ | DRD2 | P14416 | 14/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139219 | 0.90 | HTR1A (0.37) | HTR2AHTR1ADRD2KCNH2HTR2C | |
| SCHEMBL9142932 | 0.90 | ALDH1A1 (0.41) | HTR2AHTR1ADRD2KCNH2HTR2C | |
| SCHEMBL8803882 | 0.85 | USP2 (0.35) | HTR2AHTR1ADRD2KCNH2HTR2C | |
| SCHEMBL8803940 | 0.85 | KCNH2 (0.40) | HTR2AHTR1ADRD2KCNH2HTR2C | |
| SCHEMBL9136776 | 0.85 | ALDH1A1 (0.43) | HTR2AHTR1ADRD2KCNH2HTR2C | |
| Hydrochloric Acid SCHEMBL9247876 | 0.84 | KCNH2 (0.39) | HTR2AHTR1ADRD2KCNH2HTR2C | |
| SCHEMBL9137947 | 0.84 | ALDH1A1 (0.46) | HTR2AHTR1ADRD2KCNH2HTR2C | |
| SCHEMBL8806540 | 0.80 | MAPT (0.47) | HTR2AHTR1ADRD2HTR2CADRA1A | |
| SCHEMBL8805764 | 0.80 | KCNH2 (0.37) | HTR2AHTR1ADRD2KCNH2HTR2C | |
| SCHEMBL9138352 | 0.71 | BACE1 (0.37) | HTR2AHTR1ADRD2KCNH2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647231-B1 | N-SUBSTITUTED 3-AZABICYCLO[3.2.0]HEPTANE DERIVATIVES USEFUL AS NEUROLEPTIC AGENTS, ETC. | BASF AG (DE) | 1997-08-27 | — | — | EP | disclosed |
| US-5475105-A | N-substituted azabicycloheptane derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |