Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 11/20 | 0.34 |
| ▸ | DRD2 | P14416 | 11/20 | 0.34 |
| ▸ | HTR2A | P28223 | 11/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139219 | 0.95 | HTR1A (0.37) | HPGDHTR1ADRD2HTR2ACYP2C19 | |
| SCHEMBL8803818 | 0.85 | HTR2A (0.38) | HPGDHTR1ADRD2HTR2AKCNH2 | |
| SCHEMBL9136776 | 0.85 | ALDH1A1 (0.43) | USP2HPGDHSD17B10HTR1ADRD2 | |
| SCHEMBL9142932 | 0.84 | ALDH1A1 (0.41) | HTR1ADRD2HTR2ACYP2C19GAA | |
| SCHEMBL8805764 | 0.84 | KCNH2 (0.37) | HPGDHSD17B10HTR1ADRD2HTR2A | |
| SCHEMBL8804674 | 0.83 | CARM1 (0.34) | DRD2HTR2AKCNH2HTR2CCHRNA7 | |
| SCHEMBL8804882 | 0.81 | ADRA2A (0.44) | POLBHPGDHSD17B10HTR1ADRD2 | |
| SCHEMBL8804471 | 0.80 | HTR2A (0.45) | POLBHSD17B10HTR1ADRD2HTR2A | |
| SCHEMBL8804496 | 0.80 | ADRA2A (0.50) | POLBHPGDHTR1ADRD2HTR2A | |
| SCHEMBL8803940 | 0.80 | KCNH2 (0.40) | HPGDHSD17B10HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647231-B1 | N-SUBSTITUTED 3-AZABICYCLO[3.2.0]HEPTANE DERIVATIVES USEFUL AS NEUROLEPTIC AGENTS, ETC. | BASF AG (DE) | 1997-08-27 | — | — | EP | disclosed |
| US-5475105-A | N-substituted azabicycloheptane derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |