Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 8/20 | 0.34 |
| ▸ | HTR2A | P28223 | 8/20 | 0.34 |
| ▸ | HTR1A | P08908 | 7/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9136776 | 0.90 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL8803940 | 0.90 | KCNH2 (0.40) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL9142932 | 0.90 | ALDH1A1 (0.41) | ALDH1A1MAPTCYP2C9DRD2HTR2A | |
| Hydrochloric Acid SCHEMBL9247876 | 0.89 | KCNH2 (0.39) | ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL8806205 | 0.85 | DRD2 (0.46) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL8805764 | 0.84 | KCNH2 (0.37) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL9139219 | 0.84 | HTR1A (0.37) | ALDH1A1KDM4EHPGDMAPTCYP2C9 | |
| SCHEMBL8804186 | 0.80 | PKM (0.46) | ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL8803882 | 0.78 | USP2 (0.35) | HPGDHSD17B10POLBUSP2CYP2C9 | |
| SCHEMBL8803158 | 0.76 | KCNH2 (0.51) | ALDH1A1KDM4EHPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475105-A | N-substituted azabicycloheptane derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |