Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12705779 | 0.85 | GABRA1 (0.33) | GABRA1GABRB2CYP2C19CYP2D6ALDH1A1 | |
| SCHEMBL913881 | 0.84 | GABRA1 (0.38) | GABRA1GABRB2CYP2C19CYP2D6ALDH1A1 | |
| SCHEMBL12905818 | 0.82 | IAPP (0.37) | — | |
| SCHEMBL12705787 | 0.80 | GABRA1 (0.38) | GABRA1GABRB2CYP2C19CYP2D6ALDH1A1 | |
| SCHEMBL914586 | 0.79 | GABRA1 (0.34) | GABRA1GABRB2CYP2C19CYP2D6ALDH1A1 | |
| SCHEMBL916519 | 0.78 | CYP2D6 (0.39) | GABRA1GABRB2CYP2C19CYP2D6HSD17B10 | |
| SCHEMBL914312 | 0.78 | HMGCR (0.34) | GABRA1GABRB2CYP2C19 | |
| Fluoride SCHEMBL914578 | 0.77 | GABRA1 (0.35) | GABRA1GABRB2CYP2C19CYP2D6CYP1A2 | |
| SCHEMBL12905824 | 0.75 | HMGCR (0.35) | GABRA1GABRB2CYP2C19ALDH1A1HPGD | |
| SCHEMBL914440 | 0.75 | PTPN1 (0.35) | GABRA1GABRB2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7501543-B2 | Bis[2,6-bis(methoxymethyl)phenyl]disulfide; intermediates | IM&T RESEARCH, INC. (US) | 2009-03-10 | — | — | US | claimed |
| US-20080221364-A1 | Bis[2,6-bis(methoxymethyl)phenyl]disulfide; intermediates | IM&T RESEARCH, INC. (US) | 2008-09-11 | — | — | US | claimed |
| US-20080039660-A1 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-02-14 | — | — | US | claimed |
| US-9365471-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| EP-2046735-B1 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDES AS FLUORINATING AGENTS | UBE INDUSTRIES (JP) | 2015-05-06 | — | — | EP | disclosed |
| US-20140235898-A1 | Substituted Phenylsulfur Trifluoride and Other Like Fluorinating Agents | UBE INDUSTRIES, LTD. (JP) | 2014-08-21 | — | — | US | disclosed |
| US-8710270-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2014-04-29 | — | — | US | disclosed |
| US-7919635-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2011-04-05 | — | — | US | disclosed |
| US-7919635-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2011-04-05 | — | — | US | disclosed |
| US-20110009672-A1 | Substituted Phenylsulfur Trifluoride and Other Like Fluorinating Agents | IM&T RESEARCH, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| US-20090203924-A1 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | IM&T RESEARCH, INC. (US) | 2009-08-13 | — | — | US | disclosed |
| US-20090203924-A1 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | IM&T RESEARCH, INC. (US) | 2009-08-13 | — | — | US | disclosed |
| US-7501543-B2 | Bis[2,6-bis(methoxymethyl)phenyl]disulfide; intermediates | IM&T RESEARCH, INC. (US) | 2009-03-10 | — | — | US | disclosed |
| US-7501543-B2 | Bis[2,6-bis(methoxymethyl)phenyl]disulfide; intermediates | IM&T RESEARCH, INC. (US) | 2009-03-10 | — | — | US | disclosed |
| US-20080221364-A1 | Bis[2,6-bis(methoxymethyl)phenyl]disulfide; intermediates | IM&T RESEARCH, INC. (US) | 2008-09-11 | — | — | US | disclosed |
| US-20080221364-A1 | Bis[2,6-bis(methoxymethyl)phenyl]disulfide; intermediates | IM&T RESEARCH, INC. (US) | 2008-09-11 | — | — | US | disclosed |
| US-7381846-B2 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| US-7381846-B2 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| US-20080039660-A1 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-02-14 | — | — | US | disclosed |
| US-20080039660-A1 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235898-A1 | Substituted Phenylsulfur Trifluoride and Other Like Fluorinating Agents | PFAS, FRS2, FBL | GABRA1 1880/4885GABRB2 1624/4885CYP2C19 2602/4885 |
| US-20110009672-A1 | Substituted Phenylsulfur Trifluoride and Other Like Fluorinating Agents | PFAS, FRS2, FBL | GABRA1 1880/4885GABRB2 1624/4885CYP2C19 2602/4885 |
| US-20080221364-A1 | Bis[2,6-bis(methoxymethyl)phenyl]disulfide; intermediates | PFAS, STS, SCLY | GABRA1 2085/4885GABRB2 1404/4885CYP2C19 882/4885 |
| US-20090203924-A1 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | PFAS, FRS2, FBL | GABRA1 1880/4885GABRB2 1624/4885CYP2C19 2602/4885 |
| US-20080039660-A1 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | TST, DDT, ESD | GABRA1 2677/4885GABRB2 1813/4885CYP2C19 997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.