SCHEMBL1415491

SCHEMBL1415491

CC(=O)Oc1nc(C=S)cs1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9143751 0.73 MEN1 (0.33) KDM4EMAPTHSD17B10
SCHEMBL11781024 0.67 ALDH1A1 (0.51) KDM4EMAPT
SCHEMBL2771532 0.63 RAB9A (0.38) KDM4EMAPT
SCHEMBL5566834 0.62 ALOX5 (0.32) MAPT
SCHEMBL1000856 0.62 ALDH1A1 (0.44) KDM4EMAPTHSD17B10
Hydrochloric Acid SCHEMBL11102564 0.61 ALDH1A1 (0.46) KDM4EMAPTHSD17B10
SCHEMBL3559527 0.61
SCHEMBL6641922 0.60 SMN1; SMN2 (0.37) KDM4EMAPTHSD17B10
SCHEMBL29350255 0.60 MAPT (0.33) MAPT
SCHEMBL6172805 0.59 L3MBTL1 (0.56) KDM4EMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2519645-B1 A culture medium for screening or enrichment of methicillin-resistant S. aureus BIO RAD INNOVATIONS (FR) 2018-08-22 EP disclosed
US-9434978-B2 Culture medium for screening or enrichment of methicillin-resistant S. aureus BIO-RAD INNOVATIONS (FR) 2016-09-06 US disclosed
US-20120322098-A1 CULTURE MEDIUM FOR SCREENING OR ENRICHMENT OF METHICILLIN-RESISTANT S. AUREUS BIO-RAD INNOVATIONS (FR) 2012-12-20 US disclosed
EP-2519645-A1 A CULTURE MEDIUM FOR SCREENING OR ENRICHMENT OF METHICILLIN-RESISTANT S. AUREUS Bio-Rad Innovations (FR) 2012-11-07 EP disclosed
WO-2011080305-A1 A CULTURE MEDIUM FOR SCREENING OR ENRICHMENT OF METHICILLIN-RESISTANT S. AUREUS BIO-RAD PASTEUR (FR) 2011-07-07 WO disclosed
EP-1543147-B2 METHOD OF DETECTING METICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS RAMBACH ALAIN (FR) 2011-03-16 EP disclosed
US-7632657-B2 Method of detecting meticillin-resistant microorganisms Rambach, Alain (FR) 2009-12-15 US disclosed
EP-1543147-B1 METHOD OF DETECTING METICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS RAMBACH ALAIN (FR) 2006-12-20 EP disclosed
US-20060035309-A1 Method of detecting meticillin-resistant micro-organisms RAMBACH, ALAIN (FR) 2006-02-16 US disclosed
EP-1543147-A1 METHOD OF DETECTING METICILLIN-RESISTANT MICRO-ORGANISMS Rambach, Alain (FR) 2005-06-22 EP disclosed
WO-2004027086-A1 METHOD OF DETECTING METICILLIN-RESISTANT MICRO-ORGANISMS RAMBACH ALAIN (FR) 2004-04-01 WO disclosed