Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12705759 | 0.85 | TP53 (0.32) | SMN1; SMN2TP53HIF1ACYP2C9CYP2C19 | |
| SCHEMBL12705761 | 0.79 | SMN1; SMN2 (0.37) | SMN1; SMN2TP53HIF1ACYP2C9CYP2C19 | |
| SCHEMBL14083173 | 0.79 | ALDH1A1 (0.38) | SMN1; SMN2TP53HIF1ACYP2C9CYP2C19 | |
| SCHEMBL7926904 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2TP53HIF1ACYP2C9CYP2C19 | |
| SCHEMBL915297 | 0.73 | SMN1; SMN2 (0.34) | SMN1; SMN2TP53HIF1ACYP2C9CYP2C19 | |
| SCHEMBL3852985 | 0.73 | SMN1; SMN2 (0.34) | SMN1; SMN2TP53HIF1ACYP2C9CYP2C19 | |
| SCHEMBL3852978 | 0.73 | SMN1; SMN2 (0.34) | SMN1; SMN2TP53HIF1ACYP2C9CYP2C19 | |
| Fluoride SCHEMBL915142 | 0.72 | CYP2C9 (0.33) | SMN1; SMN2TP53HIF1ACYP2C9CYP2C19 | |
| SCHEMBL12705903 | 0.69 | TP53 (0.32) | SMN1; SMN2TP53HIF1ACYP2C9CYP2C19 | |
| SCHEMBL915143 | 0.69 | TP53 (0.32) | SMN1; SMN2TP53HIF1ACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046735-A2 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | IM&T Research, Inc. (US) | 2009-04-15 | — | — | EP | claimed |
| US-7501543-B2 | Bis[2,6-bis(methoxymethyl)phenyl]disulfide; intermediates | IM&T RESEARCH, INC. (US) | 2009-03-10 | — | — | US | claimed |
| US-20080221364-A1 | Bis[2,6-bis(methoxymethyl)phenyl]disulfide; intermediates | IM&T RESEARCH, INC. (US) | 2008-09-11 | — | — | US | claimed |
| US-20080039660-A1 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-02-14 | — | — | US | claimed |
| WO-2008014345-A2 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | IM & T RESEARCH, INC. (US) | 2008-01-31 | — | — | WO | claimed |
| US-9365471-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| US-9365471-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| US-9365471-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| EP-2046735-B1 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDES AS FLUORINATING AGENTS | UBE INDUSTRIES (JP) | 2015-05-06 | — | — | EP | disclosed |
| EP-2046735-B1 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDES AS FLUORINATING AGENTS | UBE INDUSTRIES (JP) | 2015-05-06 | — | — | EP | disclosed |
| US-20140235898-A1 | Substituted Phenylsulfur Trifluoride and Other Like Fluorinating Agents | UBE INDUSTRIES, LTD. (JP) | 2014-08-21 | — | — | US | disclosed |
| US-20140235898-A1 | Substituted Phenylsulfur Trifluoride and Other Like Fluorinating Agents | UBE INDUSTRIES, LTD. (JP) | 2014-08-21 | — | — | US | disclosed |
| US-7381846-B2 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| US-7381846-B2 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| US-7381846-B2 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| US-20080039660-A1 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-02-14 | — | — | US | disclosed |
| US-20080039660-A1 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-02-14 | — | — | US | disclosed |
| US-20080039660-A1 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-02-14 | — | — | US | disclosed |
| WO-2008014345-A2 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | IM & T RESEARCH, INC. (US) | 2008-01-31 | — | — | WO | disclosed |
| WO-2008014345-A2 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | IM & T RESEARCH, INC. (US) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235898-A1 | Substituted Phenylsulfur Trifluoride and Other Like Fluorinating Agents | PFAS, FRS2, FBL | SMN1; SMN2 942/4885TP53 692/4885HIF1A 4733/4885 |
| US-20080221364-A1 | Bis[2,6-bis(methoxymethyl)phenyl]disulfide; intermediates | PFAS, STS, SCLY | SMN1; SMN2 752/4885TP53 1079/4885HIF1A 4762/4885 |
| US-20080039660-A1 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | TST, DDT, ESD | SMN1; SMN2 1294/4885TP53 780/4885HIF1A 4573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.