Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL943498 | 0.97 | HTR6 (0.45) | HTR6APOBEC3GCA1CA2CA7 | |
| SCHEMBL7935363 | 0.79 | HTR6 (0.47) | HTR6APOBEC3GCA1CA2CA7 | |
| SCHEMBL19110981 | 0.73 | HTR6 (0.58) | HTR6APOBEC3GCA1CA2CA7 | |
| SCHEMBL20651138 | 0.73 | HTR6 (0.43) | HTR6APOBEC3GCA1CA2CA7 | |
| SCHEMBL17804300 | 0.73 | HTR6 (0.43) | HTR6APOBEC3GCA1CA2CA7 | |
| SCHEMBL323729 | 0.73 | HTR6 (0.58) | HTR6APOBEC3GCA1CA2CA7 | |
| SCHEMBL4580427 | 0.71 | HTR6 (0.47) | HTR6APOBEC3GCA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL30184245 | 0.71 | HTR6 (0.55) | HTR6APOBEC3GCA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL930597 | 0.71 | HTR6 (0.55) | HTR6APOBEC3GCA1CA2CA7 | |
| SCHEMBL19537583 | 0.69 | HTR6 (0.53) | HTR6APOBEC3GCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113773246-B | Preparation method of 2-substituted-4-trifluoromethylpyridine | 山东省农药科学研究院 | 2023-03-31 | — | — | CN | claimed |
| CN-113773246-A | Preparation method of 2-substituted-4-trifluoromethylpyridine | 山东省农药科学研究院 | 2021-12-10 | — | — | CN | claimed |
| US-8203003-B2 | 4-fluoropyrrolidine-2-carbonyl fluoride compounds and their preparative methods | UBE INDUSTRIES, LTD. (JP) | 2012-06-19 | — | — | US | claimed |
| CN-101591371-B | Method for preparing gemcitabine or gemcitabine analogue by halogen exchange fluorination | JINKANG PHARMACEUTICAL TECHNOLOGY CO LTD | 2012-05-30 | — | — | CN | claimed |
| US-20110275833-A1 | Novel 4-Fluoropyrrolidine-2-Carbonyl Fluoride Compounds and Their Preparative Methods | UBE INDUSTRIES, LTD. (JP) | 2011-11-10 | — | — | US | claimed |
| US-20100234605-A1 | METHODS AND COMPOSITIONS FOR PRODUCING DIFLUOROMETHYLENE-AND TRIFLUOROMETHYL-CONTAINING COMPOUNDS | IM&T RESEARCH, INC. (US) | 2010-09-16 | — | — | US | claimed |
| WO-2010081014-A1 | NOVEL 4-FLUOROPYRROLIDINE-2-CARBONYL FLUORIDE COMPOUNDS AND THEIR PREPARATIVE METHODS | IM&T RESEARCH, INC. (US) | 2010-07-15 | — | — | WO | claimed |
| US-20100174096-A1 | Methods for Production of Optically Active Fluoropyrrolidine Derivatives | IM&T RESEARCH, INC. (US) | 2010-07-08 | — | — | US | claimed |
| CN-101591371-A | A kind of method for preparing gemcitabine or its analogue by halogen-exchange fluorination | JINKANG PHARMACEUTICAL TECHNOL (CN) | 2009-12-02 | — | — | CN | claimed |
| WO-2009076345-A1 | METHODS AND COMPOSITIONS FOR PRODUCING DIFLUOROMETHYLENE-AND TRIFLUOROMETHYL-CONTAINING COMPOUNDS | IM & T RESEARCH, INC. (US) | 2009-06-18 | — | — | WO | claimed |
| CN-112062670-B | Fluorination reagent and deoxidization fluorination method | 三明市海斯福化工有限责任公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-113773246-B | Preparation method of 2-substituted-4-trifluoromethylpyridine | 山东省农药科学研究院 | 2023-03-31 | — | — | CN | disclosed |
| EP-3560910-B1 | METHOD FOR MANUFACTURING DIFLUOROMETHYLENE COMPOUND | DAIKIN IND LTD (JP) | 2023-03-29 | — | — | EP | disclosed |
| CN-112174761-B | Fluorination method | 三明市海斯福化工有限责任公司 | 2023-03-24 | — | — | CN | disclosed |
| EP-4097089-A1 | TRIFLAZOLES AND METHODS OF MAKING THE SAME | Trinapco, Inc (US) | 2022-12-07 | — | — | EP | disclosed |
| US-4120961-A | ANTIHELMINTICS, CNS ACITVITY | E. MERCK (DE) | 1978-10-17 | — | — | US | disclosed |
| US-4113867-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1978-09-12 | — | — | US | disclosed |
| US-4051243-A | RING SUBSTITUTED PYRAZINO-ISOQUINOLINE DERIVATIVES AND THEIR PREPARATION | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-4001411-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-01-04 | — | — | US | disclosed |
| US-3976691-A | Dialkylaminosulfur trifluorides as fluorinating agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275833-A1 | Novel 4-Fluoropyrrolidine-2-Carbonyl Fluoride Compounds and Their Preparative Methods | PFAS, AFF4, PAICS | HTR6 2866/4885APOBEC3G 2449/4885CA1 701/4885 |
| US-20100174096-A1 | Methods for Production of Optically Active Fluoropyrrolidine Derivatives | QDPR, FDPS, DPYD | HTR6 1329/4885APOBEC3G 1926/4885CA1 2530/4885 |
| US-20100234605-A1 | METHODS AND COMPOSITIONS FOR PRODUCING DIFLUOROMETHYLENE-AND TRIFLUOROMETHYL-CONTAINING COMPOUNDS | FDPS, PFAS, FBL | HTR6 2664/4885APOBEC3G 744/4885CA1 2374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.