Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL943616 | 1.00 | ALDH1A1 (0.40) | ALDH1A1TDP1TSHRCA1CA2 | |
| Fluoride SCHEMBL915048 | 1.00 | ALDH1A1 (0.40) | ALDH1A1TDP1TSHRCA1CA2 | |
| Fluoride SCHEMBL943618 | 1.00 | ALDH1A1 (0.40) | ALDH1A1TDP1TSHRCA1CA2 | |
| Hydrochloric Acid SCHEMBL1847110 | 0.96 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRCA1CA2 | |
| Hydrochloric Acid SCHEMBL943271 | 0.96 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRCA1CA2 | |
| SCHEMBL2556 | 0.96 | — | — | |
| Boric Acid SCHEMBL2460986 | 0.87 | CA4 (0.43) | ALDH1A1TDP1CA1CA2CA9 | |
| SCHEMBL997121 | 0.74 | ALDH1A1 (0.60) | ALDH1A1TDP1CA1CA2ALOX12 | |
| SCHEMBL149337 | 0.74 | ALDH1A1 (0.60) | ALDH1A1TDP1CA1CA2ALOX12 | |
| SCHEMBL10598460 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113773246-B | Preparation method of 2-substituted-4-trifluoromethylpyridine | 山东省农药科学研究院 | 2023-03-31 | — | — | CN | claimed |
| CN-113773246-A | Preparation method of 2-substituted-4-trifluoromethylpyridine | 山东省农药科学研究院 | 2021-12-10 | — | — | CN | claimed |
| US-8203003-B2 | 4-fluoropyrrolidine-2-carbonyl fluoride compounds and their preparative methods | UBE INDUSTRIES, LTD. (JP) | 2012-06-19 | — | — | US | claimed |
| US-20110275833-A1 | Novel 4-Fluoropyrrolidine-2-Carbonyl Fluoride Compounds and Their Preparative Methods | UBE INDUSTRIES, LTD. (JP) | 2011-11-10 | — | — | US | claimed |
| US-20100234605-A1 | METHODS AND COMPOSITIONS FOR PRODUCING DIFLUOROMETHYLENE-AND TRIFLUOROMETHYL-CONTAINING COMPOUNDS | IM&T RESEARCH, INC. (US) | 2010-09-16 | — | — | US | claimed |
| WO-2010081014-A1 | NOVEL 4-FLUOROPYRROLIDINE-2-CARBONYL FLUORIDE COMPOUNDS AND THEIR PREPARATIVE METHODS | IM&T RESEARCH, INC. (US) | 2010-07-15 | — | — | WO | claimed |
| US-20100174096-A1 | Methods for Production of Optically Active Fluoropyrrolidine Derivatives | IM&T RESEARCH, INC. (US) | 2010-07-08 | — | — | US | claimed |
| WO-2009076345-A1 | METHODS AND COMPOSITIONS FOR PRODUCING DIFLUOROMETHYLENE-AND TRIFLUOROMETHYL-CONTAINING COMPOUNDS | IM & T RESEARCH, INC. (US) | 2009-06-18 | — | — | WO | claimed |
| CN-113773246-B | Preparation method of 2-substituted-4-trifluoromethylpyridine | 山东省农药科学研究院 | 2023-03-31 | — | — | CN | disclosed |
| EP-3560910-B1 | METHOD FOR MANUFACTURING DIFLUOROMETHYLENE COMPOUND | DAIKIN IND LTD (JP) | 2023-03-29 | — | — | EP | disclosed |
| EP-4097089-A1 | TRIFLAZOLES AND METHODS OF MAKING THE SAME | Trinapco, Inc (US) | 2022-12-07 | — | — | EP | disclosed |
| US-11377407-B2 | Method for producing difluoromethylene compound | DAIKIN INDUSTRIES, LTD. (JP) | 2022-07-05 | — | — | US | disclosed |
| US-11242322-B2 | Triflazoles and methods of making the same | TRINAPCO, INC. (US) | 2022-02-08 | — | — | US | disclosed |
| CN-113773246-A | Preparation method of 2-substituted-4-trifluoromethylpyridine | 山东省农药科学研究院 | 2021-12-10 | — | — | CN | disclosed |
| US-4141978-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-02-27 | — | — | US | disclosed |
| US-4120961-A | ANTIHELMINTICS, CNS ACITVITY | E. MERCK (DE) | 1978-10-17 | — | — | US | disclosed |
| US-4113867-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1978-09-12 | — | — | US | disclosed |
| US-4051243-A | RING SUBSTITUTED PYRAZINO-ISOQUINOLINE DERIVATIVES AND THEIR PREPARATION | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-4001411-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-01-04 | — | — | US | disclosed |
| US-3976691-A | Dialkylaminosulfur trifluorides as fluorinating agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275833-A1 | Novel 4-Fluoropyrrolidine-2-Carbonyl Fluoride Compounds and Their Preparative Methods | PFAS, AFF4, PAICS | ALDH1A1 916/4885TDP1 683/4885TSHR 2379/4885 |
| US-20100174096-A1 | Methods for Production of Optically Active Fluoropyrrolidine Derivatives | QDPR, FDPS, DPYD | ALDH1A1 600/4885TDP1 2743/4885TSHR 2800/4885 |
| US-20100234605-A1 | METHODS AND COMPOSITIONS FOR PRODUCING DIFLUOROMETHYLENE-AND TRIFLUOROMETHYL-CONTAINING COMPOUNDS | FDPS, PFAS, FBL | ALDH1A1 2855/4885TDP1 1576/4885TSHR 2090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.