Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Nitrous Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrous Acid SCHEMBL78136 | 0.94 | — | — | |
| Nitrous Acid SCHEMBL28907146 | 0.88 | ALDH1A1 (0.67) | ALDH1A1ALOX15TDP1 | |
| Nitrous Acid SCHEMBL3144393 | 0.88 | ALDH1A1 (0.67) | ALDH1A1ALOX15TDP1 | |
| Nitrous Acid SCHEMBL28351527 | 0.88 | — | — | |
| Nitrous Acid SCHEMBL715656 | 0.88 | — | — | |
| Nitrous Acid SCHEMBL28362201 | 0.88 | ALDH1A1 (0.67) | ALDH1A1ALOX15TDP1 | |
| Nitrous Acid SCHEMBL28433610 | 0.88 | ALDH1A1 (0.88) | ALDH1A1ALOX15TDP1 | |
| Nitrous Acid SCHEMBL15515206 | 0.88 | — | — | |
| Nitrous Acid SCHEMBL9063371 | 0.88 | ALDH1A1 (0.67) | ALDH1A1ALOX15TDP1 | |
| Nitrous Acid SCHEMBL9063361 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5427819-A | Corrosion inhibiting repair and rehabilitation treatment process for reinforced concrete structures | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1995-06-27 | — | — | US | disclosed |
| US-4398959-A | REINFORCED CONCRETE | W. R. GRACE & CO. (US) | 1983-08-16 | — | — | US | disclosed |