Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053887 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MAPTKCNH2TDP1 | |
| SCHEMBL9053600 | 0.76 | LMNA (0.35) | ALDH1A1MAPT | |
| SCHEMBL11812673 | 0.75 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL9054287 | 0.75 | ALDH1A1 (0.30) | ALDH1A1MAPTKCNH2TDP1 | |
| SCHEMBL9053704 | 0.74 | — | — | |
| SCHEMBL9495401 | 0.63 | ALDH1A1 (0.32) | ALDH1A1MAPT | |
| SCHEMBL9495397 | 0.63 | ALDH1A1 (0.32) | ALDH1A1MAPT | |
| SCHEMBL9492962 | 0.62 | — | — | |
| SCHEMBL9053874 | 0.61 | LMNA (0.49) | ALDH1A1MAPT | |
| SCHEMBL29780034 | 0.61 | LMNA (0.49) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399576-A | Rheumatic diseases | CIBA-GEIGY CORPORATION (US) | 1995-03-21 | — | — | US | disclosed |
| US-5378719-A | Antiarthritic agents; rheumatic diseases | CIBA-GEIGY CORPORATION (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0548017-A1 | Thiazoles | CIBA-GEIGY AG (CH) | 1993-06-23 | — | — | EP | disclosed |
| EP-0548018-A1 | Imidazoles | CIBA-GEIGY AG (CH) | 1993-06-23 | — | — | EP | disclosed |