Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10890714 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPT | |
| SCHEMBL9053600 | 0.76 | LMNA (0.35) | ALDH1A1MAPT | |
| SCHEMBL9152818 | 0.75 | ALDH1A1 (0.30) | ALDH1A1MAPTKCNH2TDP1 | |
| SCHEMBL9054508 | 0.74 | — | — | |
| SCHEMBL10815382 | 0.72 | — | — | |
| SCHEMBL10810313 | 0.70 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL9494024 | 0.68 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL9494018 | 0.68 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL10726048 | 0.68 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL9492368 | 0.67 | ALDH1A1 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508955-B1 | Use of 2-iminothiazolidin-4-one derivatives as new medicaments | CIBA GEIGY AG (CH) | 1996-06-19 | — | — | EP | claimed |
| EP-0508955-A1 | Use of 2-iminothiazolidin-4-one derivatives as new medicaments | CIBA-GEIGY AG (CH) | 1992-10-14 | — | — | EP | claimed |
| EP-0508955-B1 | Use of 2-iminothiazolidin-4-one derivatives as new medicaments | CIBA GEIGY AG (CH) | 1996-06-19 | — | — | EP | disclosed |
| US-5229405-A | Rheumatic diseases | CIBA-GEIGY CORPORATION (US) | 1993-07-20 | — | — | US | disclosed |
| EP-0508955-A1 | Use of 2-iminothiazolidin-4-one derivatives as new medicaments | CIBA-GEIGY AG (CH) | 1992-10-14 | — | — | EP | disclosed |
| US-4697020-A | Derivatives of 2,4-thiazolidinedione | CIBA-GEIGY CORPORATION (US) | 1987-09-29 | — | — | US | disclosed |