Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | GFRA2 | O00451 | 1/20 | 0.36 |
| ▸ | GFRA3 | O60609 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9797486 | 0.84 | MEN1 (0.42) | DRD1MEN1KMT2A | |
| SCHEMBL9154713 | 0.82 | SLC6A4 (0.38) | FADS1DRD1LIPESLC6A4SLC6A2 | |
| SCHEMBL9797369 | 0.80 | SIGMAR1 (0.46) | MEN1KMT2APRMT5WDR77 | |
| SCHEMBL9797472 | 0.77 | SIGMAR1 (0.47) | PRMT5WDR77 | |
| SCHEMBL9797229 | 0.77 | LMNA (0.40) | MEN1KMT2APRMT5WDR77 | |
| SCHEMBL9797302 | 0.76 | GAA (0.42) | GAAMEN1KMT2APRMT5WDR77 | |
| SCHEMBL9797767 | 0.76 | SIGMAR1 (0.48) | SLC6A4HTR1A | |
| SCHEMBL9797514 | 0.76 | HRH3 (0.42) | DRD1SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL9156214 | 0.74 | CYP3A4 (0.50) | — | |
| Oxalic Acid SCHEMBL9797281 | 0.73 | KDM2B (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202319-A | Antidepressants | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-04-13 | — | — | US | claimed |
| EP-0534344-B1 | Substituted 3-amino-2,3,4,5-tetrahydro-1-aryloxy-3-benzazepines, a process for their preparation and their use as modulators of neurotransmitter function | HOECHST ROUSSEL PHARMA (US) | 1995-02-15 | — | — | EP | disclosed |
| US-5202319-A | Antidepressants | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-04-13 | — | — | US | disclosed |
| EP-0534344-A1 | Substituted 3-amino-2,3,4,5-tetrahydro-1-aryloxy-3-benzazepines, a process for their preparation and their use as modulators of neurotransmitter function | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-03-31 | — | — | EP | disclosed |