Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9797281 | 0.94 | KDM2B (0.46) | SIGMAR1KDM2BHRH3OPRK1THRB | |
| SCHEMBL9797369 | 0.84 | SIGMAR1 (0.46) | SIGMAR1KDM2BHRH3PRMT5WDR77 | |
| SCHEMBL9797229 | 0.84 | LMNA (0.40) | SIGMAR1HRH3PRMT5WDR77LMNA | |
| SCHEMBL9797302 | 0.83 | GAA (0.42) | SIGMAR1PRMT5WDR77LMNAMAPK1 | |
| SCHEMBL9797767 | 0.83 | SIGMAR1 (0.48) | SIGMAR1 | |
| SCHEMBL9797486 | 0.82 | MEN1 (0.42) | SIGMAR1CYP2D6 | |
| SCHEMBL9154713 | 0.80 | SLC6A4 (0.38) | SIGMAR1PRMT5WDR77LMNAMAPK1 | |
| SCHEMBL9797514 | 0.80 | HRH3 (0.42) | SIGMAR1HRH1CYP2D6HRH3OPRK1 | |
| Oxalic Acid SCHEMBL9797491 | 0.79 | OPRM1 (0.48) | SIGMAR1HRH3 | |
| SCHEMBL9797184 | 0.78 | SIGMAR1 (0.45) | SIGMAR1KDM2BHRH1CYP2D6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988690-A | Antidepressants | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-01-29 | — | — | US | claimed |