Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | GALE | Q14376 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL920519 | 0.79 | ADAM17 (0.46) | — | |
| SCHEMBL11483215 | 0.78 | KCNH2 (0.50) | KCNH2NR1I2ADRA2AADORA3ADRA2B | |
| SCHEMBL919681 | 0.78 | MTNR1A (0.43) | KCNH2KDM4EALDH1A1 | |
| SCHEMBL9157543 | 0.77 | KCNH2 (0.36) | KCNH2NR1I2ADRA2AADORA3ADRA2B | |
| SCHEMBL920286 | 0.76 | ALDH1A1 (0.38) | KCNH2KDM4EALDH1A1 | |
| SCHEMBL22494 | 0.76 | SYK (0.37) | KDM4EALDH1A1CA12CA1CA9 | |
| SCHEMBL8092225 | 0.75 | KDM4E (0.53) | KCNH2NR1I2ADRA2AADORA3ADRA2B | |
| SCHEMBL11478548 | 0.75 | KCNH2 (0.40) | KCNH2NR1I2ADRA2AADORA3ADRA2B | |
| SCHEMBL122928 | 0.74 | CA12 (0.48) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL921879 | 0.73 | KCNH2 (0.42) | KCNH2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443513-B1 | Azoxy compounds | KOWA CO (JP) | 1995-02-22 | — | — | EP | disclosed |
| US-5264559-A | Fungicides | KOWA COMPANY LTD. (JP) | 1993-11-23 | — | — | US | disclosed |
| EP-0443513-A2 | Azoxy compounds | KOWA COMPANY, LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |