Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8883302 | 0.82 | MAPT (0.46) | MAPTLMNANPSR1HTTGAA | |
| SCHEMBL9368620 | 0.82 | ALDH1A1 (0.45) | MAPTLMNAHTTGAACYP1A2 | |
| SCHEMBL11060398 | 0.80 | GAA (0.38) | MAPTMAPK1LMNANPSR1HTT | |
| SCHEMBL9155654 | 0.79 | MAPK1 (0.42) | MAPTMAPK1LMNANPSR1CYP1A2 | |
| SCHEMBL9480478 | 0.76 | GAA (0.47) | MAPTLMNANPSR1HTTGAA | |
| SCHEMBL3950171 | 0.72 | KDM4E (0.39) | MAPTLMNANPSR1HTTGAA | |
| SCHEMBL11699857 | 0.72 | ALDH1A1 (0.37) | MAPTLMNANPSR1HTTGAA | |
| SCHEMBL2910688 | 0.72 | LMNA (0.47) | MAPTLMNANPSR1HTTCYP1A2 | |
| SCHEMBL11795513 | 0.68 | POLB (0.48) | MAPTNPSR1HTTCYP1A2KMT2A | |
| SCHEMBL13012211 | 0.67 | GAA (0.37) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100285963-A1 | SUBSTITUTED FLUOROALKOXYPHENYLSULFONYLUREAS | MULLER KLAUS-HELMUT | 2010-11-11 | — | — | US | disclosed |
| US-20100285963-A1 | SUBSTITUTED FLUOROALKOXYPHENYLSULFONYLUREAS | MULLER KLAUS-HELMUT | 2010-11-11 | — | — | US | disclosed |
| US-20100285963-A1 | SUBSTITUTED FLUOROALKOXYPHENYLSULFONYLUREAS | MULLER KLAUS-HELMUT | 2010-11-11 | — | — | US | disclosed |
| US-7723266-B2 | Substituted aryl sulphony(thio)ureas used as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2010-05-25 | — | — | US | disclosed |
| US-7723266-B2 | Substituted aryl sulphony(thio)ureas used as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2010-05-25 | — | — | US | disclosed |
| US-7723266-B2 | Substituted aryl sulphony(thio)ureas used as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2010-05-25 | — | — | US | disclosed |
| US-7723267-B2 | Substituted fluoroalcoxyphenylsulfonylurea | BAYER CROPSCIENCE AG (DE) | 2010-05-25 | — | — | US | disclosed |
| US-7723267-B2 | Substituted fluoroalcoxyphenylsulfonylurea | BAYER CROPSCIENCE AG (DE) | 2010-05-25 | — | — | US | disclosed |
| US-7723267-B2 | Substituted fluoroalcoxyphenylsulfonylurea | BAYER CROPSCIENCE AG (DE) | 2010-05-25 | — | — | US | disclosed |
| US-20080300138-A1 | Dioxazinyl-Substituted Thienylsulphonylaminocarbonyl Compounds | GESING ERNST R F | 2008-12-04 | — | — | US | disclosed |
| WO-2003056922-A1 | SUBSTITUTED THIAZOLYL SULFONYL UREA COMPOUNDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-07-17 | — | — | WO | disclosed |
| WO-2002072560-A1 | SUBSTITUTED FLUOROALCOXYPHENYLSULFONYLUREA | BAYER CROPSCIENCE AG (DE) | 2002-09-19 | — | — | WO | disclosed |
| US-6451737-B1 | N-(4,6-DIMETHYL-PYRIMIDIN-2-YL)-N'-(2-METHOXY-6-TRIFLUOROMETHY L-PHENYLSULPHONYL)-UREA | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-17 | — | — | US | disclosed |
| US-6451738-B1 | Substituted thienyl(Amino)-sulphonyl(thio)ureas as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-17 | — | — | US | disclosed |
| US-20020068681-A1 | Substituted thienyl(amino)-sulphonyl(thio)ureas as herbicides | GESING ERNST RUDOLF F (DE) | 2002-06-06 | — | — | US | disclosed |
| US-6303541-B1 | Substituted thienyl(amino)sulphonyl(thio)ureas as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2001-10-16 | — | — | US | disclosed |
| EP-0942652-A1 | SUBSTITUTED THIENYL(AMINO)SULPHONYL(THIO)UREAS AS HERBICIDES | BAYER AG (DE) | 1999-09-22 | — | — | EP | disclosed |
| EP-0885200-A1 | SUBSTITUTED ARYL SULPHONYL(THIO)UREAS USED AS HERBICIDES | BAYER AG (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1998025467-A1 | SUBSTITUTED THIENYL(AMINO)SULPHONYL(THIO)UREAS AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-18 | — | — | WO | disclosed |
| WO-1997032861-A1 | SUBSTITUTED ARYL SULPHONYL(THIO)UREAS USED AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020068681-A1 | Substituted thienyl(amino)-sulphonyl(thio)ureas as herbicides | TST, DDT, TMT1A | MAPT 3879/4885MAPK1 3202/4885LMNA 4764/4885 |
| US-20080300138-A1 | Dioxazinyl-Substituted Thienylsulphonylaminocarbonyl Compounds | DDT, DHX35, DHX15 | MAPT 4860/4885MAPK1 3512/4885LMNA 3510/4885 |
| US-20100285963-A1 | SUBSTITUTED FLUOROALKOXYPHENYLSULFONYLUREAS | PFAS, CBR3, CBR1 | MAPT 4573/4885MAPK1 2047/4885LMNA 3204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.