Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9152881 | 0.73 | MAOA (0.32) | ALDH1A1LMNAMAPTTSHRMAPK1 | |
| SCHEMBL2474639 | 0.73 | ALDH1A1 (0.33) | ALDH1A1LMNATSHR | |
| SCHEMBL6493827 | 0.69 | TSHR (0.38) | ALDH1A1LMNAMAPTTSHRMAPK1 | |
| SCHEMBL9263550 | 0.67 | CYP3A4 (0.44) | ALDH1A1LMNAMAPTTSHRMAPK1 | |
| SCHEMBL1449734 | 0.66 | TSHR (0.43) | DRD1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL2662444 | 0.65 | SLC6A4 (0.41) | ALDH1A1LMNAMAPTTSHRMAPK1 | |
| SCHEMBL7947544 | 0.64 | RXRA (0.45) | DRD1CYP3A4TDP1 | |
| SCHEMBL4898935 | 0.63 | TDP1 (0.46) | DRD1ALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL17782028 | 0.62 | TDP1 (0.46) | ALDH1A1LMNAMAPTTSHRMAPK1 | |
| 1,4-Dichlorobenzene SCHEMBL11803922 | 0.61 | CYP3A4 (0.71) | ALDH1A1LMNATSHRMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639187-A1 | PHENYLDERIVATE AS INHIBITORS OF ATP CITRATE LYASE | SMITHKLINE BEECHAM PLC (GB) | 1995-02-22 | — | — | EP | disclosed |