Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158254 | 0.96 | RIPK1 (0.48) | RIPK1UTS2RPPIDHSD11B1AGTR2 | |
| SCHEMBL9157264 | 0.85 | HPGD (0.46) | OPRD1 | |
| SCHEMBL9156240 | 0.84 | OPRD1 (0.45) | RIPK1UTS2RHSD11B1AGTR2OPRD1 | |
| SCHEMBL9152133 | 0.82 | NPC1 (0.47) | UTS2RHSD11B1OPRD1DPP4DPP8 | |
| SCHEMBL9154470 | 0.80 | OPRD1 (0.45) | RIPK1UTS2RPPIDOPRD1EPHX2 | |
| SCHEMBL9471748 | 0.79 | SMN1; SMN2 (0.46) | OPRD1 | |
| SCHEMBL9152726 | 0.77 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL9152718 | 0.77 | PPID (0.39) | UTS2RPPIDHSD11B1AGTR2EPHX2 | |
| SCHEMBL9157922 | 0.75 | PRMT5 (0.47) | UTS2RPPIDEPHX2PRMT5WDR77 | |
| SCHEMBL9160617 | 0.75 | PPID (0.43) | PPIDEPHX2PRMT5WDR77PARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |