Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PPID | Q08752 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156611 | 0.97 | ALDH1A1 (0.45) | PRMT5WDR77DRD2DRD4DRD3 | |
| SCHEMBL9158560 | 0.90 | MEN1 (0.46) | PRMT5WDR77UTS2RALDH1A1DCUN1D1 | |
| SCHEMBL9160617 | 0.89 | PPID (0.43) | PRMT5WDR77PPIDPARP14CPT2 | |
| SCHEMBL9156594 | 0.88 | PPID (0.43) | PRMT5WDR77PPIDPARP14CPT2 | |
| SCHEMBL9471547 | 0.85 | ALDH1A1 (0.50) | ALDH1A1RAB9AEPHX2CCKBR | |
| SCHEMBL9158371 | 0.84 | RAB9A (0.51) | ALDH1A1RAB9AEPHX2CCKBR | |
| SCHEMBL9159792 | 0.81 | EPHX2 (0.50) | DCUN1D1EPHX2CCKBR | |
| SCHEMBL9156842 | 0.81 | DCUN1D1 (0.42) | PRMT5WDR77ALDH1A1DCUN1D1NPC1 | |
| SCHEMBL9156835 | 0.81 | DCUN1D1 (0.42) | PRMT5WDR77ALDH1A1DCUN1D1NPC1 | |
| SCHEMBL9162155 | 0.80 | CCKBR (0.44) | ALDH1A1DCUN1D1NPC1RAB9AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |