Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157966 | 0.85 | ALDH1A1 (0.58) | HPGDALDH1A1KMT2APOLBMAPT | |
| SCHEMBL9157740 | 0.84 | KMT2A (0.66) | HPGDALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL9152136 | 0.81 | BCHE (0.54) | ALDH1A1KMT2AMEN1THRB | |
| SCHEMBL9135817 | 0.81 | POLB (0.69) | HPGDALDH1A1LMNAHTTKMT2A | |
| SCHEMBL9158329 | 0.80 | GAA (0.72) | HPGDALDH1A1LMNAHTTKMT2A | |
| SCHEMBL9154021 | 0.80 | ALDH1A1 (0.55) | ALDH1A1LMNAKMT2APOLBMAPT | |
| SCHEMBL9153787 | 0.80 | KMT2A (0.55) | HPGDALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL9158053 | 0.79 | HPGD (0.51) | HPGDALDH1A1LMNAPOLBTSHR | |
| SCHEMBL9159221 | 0.79 | MEN1 (0.52) | ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL8860030 | 0.79 | CA12 (0.60) | HPGDALDH1A1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |