Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158437 | 0.80 | HPGD (0.53) | POLBHTTLMNAALDH1A1MAPT | |
| SCHEMBL9157740 | 0.79 | KMT2A (0.66) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9157966 | 0.75 | ALDH1A1 (0.58) | GAAPOLBALDH1A1MAPTMEN1 | |
| SCHEMBL9153787 | 0.74 | KMT2A (0.55) | POLBALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9152136 | 0.73 | BCHE (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8860030 | 0.73 | CA12 (0.60) | GAANPSR1POLBTDP1ALDH1A1 | |
| SCHEMBL9156584 | 0.72 | MAPT (0.50) | POLBTDP1HDAC1HDAC3HDAC4 | |
| SCHEMBL9152837 | 0.72 | POLB (0.57) | POLBTDP1HDAC1HDAC6ALDH1A1 | |
| SCHEMBL9154021 | 0.72 | ALDH1A1 (0.55) | GAANPSR1POLBHDAC1HDAC6 | |
| SCHEMBL9159221 | 0.71 | MEN1 (0.52) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |