Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157740 | 0.92 | KMT2A (0.66) | KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL9157966 | 0.90 | ALDH1A1 (0.58) | KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL9159221 | 0.86 | MEN1 (0.52) | KMT2AMEN1SMN1; SMN2ALDH1A1AKR1B1 | |
| SCHEMBL9152136 | 0.81 | BCHE (0.54) | KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9153770 | 0.81 | SMN1; SMN2 (0.51) | KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL9157633 | 0.81 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1POLBNPC1 | |
| SCHEMBL9158437 | 0.80 | HPGD (0.53) | KMT2AMEN1MAPK1ALDH1A1POLB | |
| SCHEMBL9158114 | 0.79 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2ALDH1A1ATM | |
| SCHEMBL8860030 | 0.79 | CA12 (0.60) | KMT2AMEN1ALDH1A1AKR1B1POLB | |
| SCHEMBL9152837 | 0.78 | POLB (0.57) | KMT2AMEN1SMN1; SMN2ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |