Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9159223 | 0.96 | PABPC1 (0.35) | PABPC1CTDSP1GAA | |
| SCHEMBL9162408 | 0.82 | PABPC1 (0.38) | PABPC1CTDSP1GAA | |
| SCHEMBL9159381 | 0.82 | PABPC1 (0.38) | PABPC1CTDSP1GAA | |
| SCHEMBL9430245 | 0.79 | PABPC1 (0.36) | PABPC1CTDSP1GAA | |
| SCHEMBL29392716 | 0.75 | PABPC1 (0.36) | PABPC1CTDSP1GAA | |
| SCHEMBL26054727 | 0.75 | PABPC1 (0.36) | PABPC1CTDSP1GAA | |
| SCHEMBL9156303 | 0.75 | CA2 (0.33) | — | |
| SCHEMBL9331683 | 0.73 | PABPC1 (0.32) | PABPC1CTDSP1GAA | |
| SCHEMBL9162623 | 0.72 | CA2 (0.33) | — | |
| SCHEMBL14932765 | 0.72 | PABPC1 (0.36) | PABPC1CTDSP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426253-B1 | Process for the separation of R and S-2,2R1, R2-1,3-dioxolane-4-carboxylic acid | SHELL INT RESEARCH (NL) | 1995-02-22 | — | — | EP | disclosed |
| US-5164519-A | Process for the separation of R and S-2,2-R1,R2 -1,3-dioxolane-4-carboxylic acid | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1992-11-17 | — | — | US | disclosed |
| EP-0426253-A1 | Process for the separation of R and S-2,2R1, R2-1,3-dioxolane-4-carboxylic acid | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-05-08 | — | — | EP | disclosed |