SCHEMBL9164047

SCHEMBL9164047

O=C1c2ccccc2C(Cl)=C(Cl)C1(Cl)Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 2/20 0.55
IDO1 P14902 1/20 0.44
DNMT1 P26358 1/20 0.44
DNMT3L Q9UJW3 1/20 0.44
DNMT3A Q9Y6K1 1/20 0.44
MAPT P10636 7/20 0.43
ALDH1A1 P00352 6/20 0.43
HTT P42858 4/20 0.43
KDM4E B2RXH2 3/20 0.43
ALOX12 P18054 3/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
LMNA P02545 3/20 0.43
TSHR P16473 2/20 0.43
MAPK1 P28482 2/20 0.43
RECQL P46063 2/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CASP1 P29466 1/20 0.43
CA7 P43166 1/20 0.43
BACE1 P56817 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11593604 0.81 S100A4 (0.70) S100A4IDO1DNMT1DNMT3LDNMT3A
SCHEMBL2599169 0.71 S100A4 (1.00) S100A4IDO1DNMT1DNMT3LDNMT3A
SCHEMBL6415438 0.71 IDO1 (0.52) S100A4IDO1DNMT1DNMT3LDNMT3A
SCHEMBL29634717 0.71 IDO1 (0.52) S100A4IDO1DNMT1DNMT3LDNMT3A
SCHEMBL7620046 0.70
SCHEMBL9557721 0.66 IDO1 (0.56) S100A4IDO1DNMT1DNMT3LDNMT3A
SCHEMBL2637337 0.66 ALDH1A1 (0.56) MAPTALDH1A1KDM4EALOX12TSHR
SCHEMBL11592777 0.66 RECQL (0.55) S100A4IDO1DNMT1DNMT3LDNMT3A
SCHEMBL29588249 0.66 RECQL (0.55) S100A4IDO1DNMT1DNMT3LDNMT3A
SCHEMBL22465886 0.65 S100A4 (0.45) S100A4IDO1DNMT1DNMT3LDNMT3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0016061-B1 ORGANIC HALOGEN COMPOUNDS USED IN DIRECT POSITIVE EMULSIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-04-10 EP claimed
EP-0016061-A4 ORGANIC HALOGEN COMPOUNDS USED IN DIRECT POSITIVE EMULSIONS. DU PONT (US) 1981-08-27 EP claimed
EP-0016061-A1 ORGANIC HALOGEN COMPOUNDS USED IN DIRECT POSITIVE EMULSIONS. DU PONT (US) 1980-10-01 EP claimed
WO-1980000040-A1 ORGANIC HALOGEN COMPOUNDS USED IN DIRECT POSITIVE EMULSIONS DU PONT (US) 1980-01-10 WO claimed
US-5473409-A Semiconductor light exposure device SONY CORPORATION (JP) 1995-12-05 US disclosed
EP-0031566-B2 PHOTOSENSITIVE NEGATIVE-WORKING TONABLE ELEMENT E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-05-29 EP disclosed
EP-0031566-B1 PHOTOSENSITIVE NEGATIVE-WORKING TONABLE ELEMENT E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-03-14 EP disclosed
US-4356252-A POLYMERIC BINDER, PHOTOINITIATOR, ACETAL, PLASTICIZING, POLYMERIC ANHYDRIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-10-26 US disclosed
US-4294909-A Photosensitive negative-working toning process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-10-13 US disclosed
US-4292394-A Process for preparing multicolor toned images on a single photosensitive layer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-09-29 US disclosed
EP-0016061-A4 ORGANIC HALOGEN COMPOUNDS USED IN DIRECT POSITIVE EMULSIONS. DU PONT (US) 1981-08-27 EP disclosed
EP-0031566-A1 Photosensitive negative-working tonable element E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-07-08 EP disclosed
EP-0016061-A1 ORGANIC HALOGEN COMPOUNDS USED IN DIRECT POSITIVE EMULSIONS. DU PONT (US) 1980-10-01 EP disclosed
WO-1980000040-A1 ORGANIC HALOGEN COMPOUNDS USED IN DIRECT POSITIVE EMULSIONS DU PONT (US) 1980-01-10 WO disclosed