SCHEMBL9164375

SCHEMBL9164375

ON=CC1=Cc2cc(Sc3ccccc3)ccc2CC1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
HPGD P15428 2/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
FGF23 Q9GZV9 2/20 0.33
BCL2 P10415 1/20 0.32
MCL1 Q07820 1/20 0.32
MAOA P21397 2/20 0.32
MAOB P27338 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9164371 1.00 ALDH1A1 (0.34) ALDH1A1HPGDMEN1MAPTHTT
SCHEMBL9164386 0.82 MAOA (0.36) ALDH1A1HPGDBCL2MCL1MAOA
SCHEMBL9159101 0.79 FGF23 (0.42) HPGDSMN1; SMN2FGF23
SCHEMBL9159093 0.79 FGF23 (0.42) HPGDSMN1; SMN2FGF23
SCHEMBL9164535 0.76 ALDH1A1 (0.40) ALDH1A1HPGDMEN1HTTKMT2A
SCHEMBL9164541 0.76 ALDH1A1 (0.40) ALDH1A1HPGDMEN1HTTKMT2A
SCHEMBL9160926 0.76 IDH1 (0.37) SMN1; SMN2FGF23
SCHEMBL9160933 0.76 IDH1 (0.37) SMN1; SMN2FGF23
SCHEMBL9162691 0.73 BCL2 (0.32) ALDH1A1HPGDBCL2MCL1MAOA
SCHEMBL9162692 0.72 ALDH1A1 (0.35) ALDH1A1HPGDSMN1; SMN2BCL2MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0408760-B1 NEW HYDROXYLAMINE DERIVATIVE FUJISAWA PHARMACEUTICAL CO (JP) 1995-03-15 EP disclosed
EP-0408760-A1 NEW HYDROXYLAMINE DERIVATIVE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-01-23 EP disclosed