Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | BAX | Q07812 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.34 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9164535 | 1.00 | ALDH1A1 (0.40) | ALDH1A1HPGDHRH3PDE4APDE4B | |
| SCHEMBL9162672 | 0.82 | MAOA (0.45) | HPGDHRH3ALOX5 | |
| SCHEMBL9162668 | 0.82 | MAOA (0.45) | HPGDHRH3ALOX5 | |
| SCHEMBL9163107 | 0.82 | HRH3 (0.41) | HPGDHRH3PDE4APDE4BPDE4C | |
| SCHEMBL9159101 | 0.79 | FGF23 (0.42) | HPGDFGF23 | |
| SCHEMBL9159093 | 0.79 | FGF23 (0.42) | HPGDFGF23 | |
| SCHEMBL9729527 | 0.76 | ALOX5 (0.51) | ALDH1A1HPGDALOX5 | |
| SCHEMBL9729533 | 0.76 | ALOX5 (0.51) | ALDH1A1HPGDALOX5 | |
| SCHEMBL9164375 | 0.76 | ALDH1A1 (0.34) | ALDH1A1HPGDHTTMEN1KMT2A | |
| SCHEMBL9160926 | 0.76 | IDH1 (0.37) | FGF23 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0408760-B1 | NEW HYDROXYLAMINE DERIVATIVE | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-03-15 | — | — | EP | disclosed |
| EP-0408760-A1 | NEW HYDROXYLAMINE DERIVATIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |