Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 3/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HNF4A | P41235 | 1/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160926 | 1.00 | IDH1 (0.37) | IDH1PARP11TACR3TACR1FGF23 | |
| SCHEMBL9162672 | 0.80 | MAOA (0.45) | CA2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL9162668 | 0.80 | MAOA (0.45) | CA2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL9159101 | 0.79 | FGF23 (0.42) | FGF23SMN1; SMN2 | |
| SCHEMBL9159093 | 0.79 | FGF23 (0.42) | FGF23SMN1; SMN2 | |
| SCHEMBL9164375 | 0.76 | ALDH1A1 (0.34) | FGF23SMN1; SMN2 | |
| SCHEMBL9164371 | 0.76 | ALDH1A1 (0.34) | FGF23SMN1; SMN2 | |
| SCHEMBL9164541 | 0.76 | ALDH1A1 (0.40) | FGF23 | |
| SCHEMBL9164535 | 0.76 | ALDH1A1 (0.40) | FGF23 | |
| SCHEMBL9160772 | 0.74 | THRB (0.40) | IDH1PARP11TACR3TACR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0408760-B1 | NEW HYDROXYLAMINE DERIVATIVE | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-03-15 | — | — | EP | disclosed |
| EP-0408760-A1 | NEW HYDROXYLAMINE DERIVATIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |