SCHEMBL319873

SCHEMBL319873

CCOC(=O)CC(=O)Cc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPID Q08752 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.50
ALDH1A1 P00352 2/20 0.50
MAPK1 P28482 1/20 0.50
PAM P19021 1/20 0.49
MGAM O43451 1/20 0.48
GAA P10253 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
TSHR P16473 1/20 0.47
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
MMP8 P22894 1/20 0.46
LTA4H P09960 1/20 0.46
MAPK8 P45983 1/20 0.46
MAPK9 P45984 1/20 0.46
MAPK10 P53779 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28280410 0.98 PPID (0.53) PPIDL3MBTL1ALDH1A1MAPK1PAM
SCHEMBL6175776 0.97 PPID (0.51) PPIDL3MBTL1ALDH1A1MAPK1PAM
SCHEMBL3240817 0.92 L3MBTL1 (0.51) PPIDL3MBTL1ALDH1A1MAPK1PAM
SCHEMBL6187830 0.90 ALDH1A1 (0.53) PPIDL3MBTL1ALDH1A1GAASMN1; SMN2
SCHEMBL15334365 0.86 GAA (0.52) L3MBTL1MGAMGAASIMGAM2
SCHEMBL1332625 0.85 ALDH1A1 (0.68) PPIDL3MBTL1ALDH1A1MAPK1PAM
SCHEMBL112999 0.85 ALDH1A1 (0.68) PPIDL3MBTL1ALDH1A1MAPK1PAM
SCHEMBL1873977 0.85 ALDH1A1 (0.68) PPIDL3MBTL1ALDH1A1MAPK1PAM
Benzene SCHEMBL28160801 0.85 ALDH1A1 (0.68) PPIDL3MBTL1ALDH1A1MAPK1PAM
SCHEMBL13054407 0.84 PPID (0.61) PPIDALDH1A1GAASMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119614529-A Short-chain dehydrogenase, engineering bacteria and application thereof in asymmetric reduction of potential chiral carbonyl compounds 杭州文德阶生物科技有限公司 2025-03-14 CN claimed
CN-116837043-A Application of reductive amination enzyme in asymmetric synthesis of chiral amine 江南大学 2023-10-03 CN claimed
CN-116837042-A Application of reductive amination enzyme in asymmetric synthesis of chiral amine 江南大学 2023-10-03 CN claimed
CN-115068619-A Preparation method of photo-thermal dual-response composite carrier, prepared composite carrier and application of composite carrier 北京化工大学 2022-09-20 CN claimed
CN-216630748-U Production device of high-purity phenylacetic acid ethyl ester 沈阳万菱生物技术有限公司 2022-05-31 CN claimed
CN-112225721-B Acid-responsive near-infrared lysosome organic small-molecule fluorescent probe and preparation method and application thereof 复旦大学 2021-09-17 CN claimed
CN-112225721-A Acid-responsive near-infrared lysosome organic small-molecule fluorescent probe and preparation method and application thereof 复旦大学 2021-01-15 CN claimed
CN-107459535-A Polysubstituted quinoline coordinated iridium hybrid compound and preparation method and application thereof 南京工业大学 2017-12-12 CN claimed
CN-106674011-A Method of synthesizing indanone derivative from dimethyl sulfoxide 南京理工大学 2017-05-17 CN claimed
EP-0912467-B1 ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE RHODIA CHIMIE SA (FR) 2002-04-24 EP claimed
US-4529704-A Carrier matric containing ketoalkanoic ester MILES LABORATORIES, INC. (US) 1985-07-16 US claimed
EP-0029915-B1 DEVICE AND METHOD FOR THE PREPARATION OF A CONTROL SOLUTION FOR KETONE DETERMINATION AND METHOD OF CALIBRATING A KETONE TEST INSTRUMENT MILES LABORATORIES, INC. (US) 1983-07-20 EP claimed
EP-0029915-A1 Device and method for the preparation of a control solution for ketone determination and method of calibrating a ketone test instrument MILES LABORATORIES, INC. (US) 1981-06-10 EP claimed
WO-2025262192-A1 QUINAZOLINE DERIVATIVES SUITABLE FOR USE AS WERNER SYNDROME HELICASE PROTEIN INHIBITORS BREAKPOINT THERAPEUTICS GMBH (DE) 2025-12-26 WO disclosed
US-12378200-B2 Oxopyridine derivatives useful as aminocarboxymuconate semialdehyde decarboxylase (ACMSD) inhibitors ORSOBIO, INC. (US) 2025-08-05 US disclosed
US-20250186441-A1 COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES OXALURX, INC. 2025-06-12 US disclosed
US-4012383-A BACTERICIDES BRISTOL-MYERS COMPANY (US) 1977-03-15 US disclosed
US-4007180-A POLYESTERS HOECHST AKTIENGESELLSCHAFT (DT) 1977-02-08 US disclosed
US-3950333-A HISTAMINE INHIBITORS, OXYALKYL, THIOALKYL, AMINOALKYL DERIVATIVES SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1976-04-13 US disclosed
US-3950353-A HISTAMINE INHIBITORS SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378200-B2 Oxopyridine derivatives useful as aminocarboxymuconate semialdehyde decarboxylase (ACMSD) inhibitors ALDH7A1, ACMSD, AMD1 PPID 203/4885L3MBTL1 2791/4885ALDH1A1 370/4885
US-20250186441-A1 COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES XDH, PNPO, OAT PPID 849/4885L3MBTL1 2665/4885ALDH1A1 543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.