Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | BRD2 | P25440 | 1/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661504 | 0.89 | SLC2A1 (0.54) | BRD4SLC2A1HTR6CYP1A2CYP2C9 | |
| SCHEMBL3507524 | 0.89 | SLC2A1 (0.54) | BRD4SLC2A1HTR6CYP1A2CYP2C9 | |
| SCHEMBL29928879 | 0.82 | CDK4 (0.53) | BRD4SLC2A1HTR6BRD2BRD3 | |
| SCHEMBL11225244 | 0.82 | CDK4 (0.53) | BRD4SLC2A1HTR6BRD2BRD3 | |
| SCHEMBL4203272 | 0.80 | SLC2A1 (0.48) | BRD4SLC2A1BRD2BRD3CYP1A2 | |
| SCHEMBL917196 | 0.78 | BRD4 (0.51) | BRD4SLC2A1BRD2BRD3CYP1A2 | |
| SCHEMBL396279 | 0.77 | HTR6 (0.66) | BRD4SLC2A1HTR6 | |
| SCHEMBL5134071 | 0.77 | HTR6 (0.66) | BRD4SLC2A1HTR6 | |
| Hydrochloric Acid SCHEMBL19896389 | 0.77 | L3MBTL1 (0.47) | BRD4SLC2A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12359735 | 0.76 | HTR6 (0.39) | BRD4HTR6BRD2BRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009428-A1 | NOVEL ANDROGENS | N.V. ORGANON (NL) | 2011-01-13 | — | — | US | disclosed |
| US-7812036-B2 | Androgens | N.V. ORGANON (NL) | 2010-10-12 | — | — | US | disclosed |
| EP-1742912-B1 | NOVEL ANDROGENS | ORGANON NV (NL) | 2010-08-25 | — | — | EP | disclosed |
| US-20070225352-A1 | Novel Androgens | PHARMACOPELA DRUG DISCOVERY, INC. (US) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225352-A1 | Novel Androgens | NR5A1, AR, SHBG | BRD4 867/4885SLC2A1 1674/4885HTR6 734/4885 |
| US-20110009428-A1 | NOVEL ANDROGENS | NR5A1, AR, NR3C2 | BRD4 688/4885SLC2A1 1766/4885HTR6 209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.