SCHEMBL9164472

SCHEMBL9164472

Nc1ccc(C2OC(=O)CC(=O)O2)cc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.40
CYP19A1 P11511 8/20 0.39
DDB1 Q16531 2/20 0.37
CRBN Q96SW2 2/20 0.37
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
MAPT P10636 2/20 0.33
GRM2 Q14416 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
RECQL P46063 1/20 0.33
SIRT1 Q96EB6 2/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL992746 0.79 MAPT (0.45) AKT1CYP19A1MEN1KMT2AMAPT
SCHEMBL28525073 0.79 MAOB (0.40) CYP19A1MEN1KMT2AMAPTALDH1A1
SCHEMBL9244468 0.79 FADS1 (0.42) CYP19A1ALDH1A1
SCHEMBL120709 0.78 MEN1 (0.48) CYP19A1MEN1KMT2AMAPTKDM4E
SCHEMBL8207399 0.77 MEN1 (0.47) CYP19A1MEN1KMT2AMAPTKDM4E
SCHEMBL3428777 0.75 LMNA (0.52) CYP19A1DDB1CRBNKMT2AMAPT
SCHEMBL28985350 0.75 ALDH1A1 (0.33) ALDH1A1RECQLLMNA
SCHEMBL10590171 0.75 CYP19A1 (0.39) CYP19A1DDB1CRBNMEN1KMT2A
SCHEMBL6175110 0.73 KMT2A (0.46) MEN1KMT2AMAPTALDH1A1RECQL
SCHEMBL5186156 0.72 MEN1 (0.43) CYP19A1MEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0507691-B1 S-triazine derivatives substituted with benzalmalonates, process for their preparation, filtering cosmetic compositions containing them and their use as UV-protectors for skin and hair OREAL (FR) 1995-03-15 EP disclosed
EP-0507691-A1 S-triazine derivatives substituted with benzalmalonates, process for their preparation, filtering cosmetic compositions containing them and their use as UV-protectors for skin and hair L'OREAL (FR) 1992-10-07 EP disclosed