SCHEMBL91649

SCHEMBL91649

C=Cc1ccc2cc(C(=O)OCOC3CCCc4ccccc43)ccc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 1/20 0.47
TAS1R1 Q7RTX1 1/20 0.47
TAOK1 Q7L7X3 1/20 0.41
TAOK3 Q9H2K8 1/20 0.41
KMT2A Q03164 3/20 0.38
POLB P06746 3/20 0.38
GAA P10253 2/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
IDO1 P14902 2/20 0.38
HTT P42858 2/20 0.37
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 2/20 0.36
FFAR1 O14842 1/20 0.36
TRPV1 Q8NER1 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL92302 0.90 TAS1R3 (0.55) TAS1R3TAS1R1KMT2APOLBGAA
SCHEMBL91654 0.80 HRH3 (0.39) TAS1R3TAS1R1KMT2APOLBMAPT
SCHEMBL91648 0.73 IDO1 (0.38) TAS1R3TAS1R1KMT2AGAAMEN1
SCHEMBL2192882 0.72 TAS1R3 (0.56) TAS1R3TAS1R1KMT2AGAAMAPT
SCHEMBL92270 0.71 IDO1 (0.47) TAS1R3TAS1R1KMT2AGAAMEN1
SCHEMBL11999054 0.69 IDO1 (0.53) TAS1R3TAS1R1IDO1ALDH1A1FFAR1
SCHEMBL16329467 0.68 CA12 (0.51) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL9891412 0.68 CYP3A4 (0.40) TAS1R3TAS1R1KMT2APOLBGAA
SCHEMBL71690 0.68 TAS1R3 (0.39) TAS1R3TAS1R1KMT2AMAPTMEN1
SCHEMBL9610298 0.68 MTNR1A (0.35) TAS1R3TAS1R1KMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129086-B2 Polymerizable compound, polymer, positive resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-06 US disclosed
US-8129086-B2 Polymerizable compound, polymer, positive resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-06 US disclosed
US-20090297979-A1 Polymerizable compound, polymer, positive resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed
US-20090297979-A1 Polymerizable compound, polymer, positive resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090297979-A1 Polymerizable compound, polymer, positive resist composition, and patterning process using the same PRRC2A, PUF60, POLR2B TAS1R3 1997/4885TAS1R1 1768/4885TAOK1 3047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.