SCHEMBL9891412

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18355102	0.94	MAPT (0.38)	CYP3A4MEN1ALDH1A1KMT2AKDM4E
	SCHEMBL9610448	0.92	SMN1; SMN2 (0.37)	CYP3A4MEN1ALDH1A1KMT2AKDM4E
	SCHEMBL2776767	0.86	TAS1R3 (0.41)	MEN1ALDH1A1KMT2AKDM4EPKM
	SCHEMBL19719109	0.80	—	—
	SCHEMBL17995089	0.80	MEN1 (0.33)	MEN1KMT2AKDM4EMAPTAKR1C3
	SCHEMBL18355103	0.80	EDNRB (0.40)	ALDH1A1MAPTSMN1; SMN2TDP1POLB
	SCHEMBL9610453	0.80	TAS1R3 (0.36)	CYP3A4MEN1ALDH1A1KMT2AKDM4E
	SCHEMBL9610358	0.76	TAS1R3 (0.36)	CYP3A4MEN1ALDH1A1KMT2AKDM4E
	SCHEMBL9610298	0.74	MTNR1A (0.35)	CYP3A4MEN1ALDH1A1KMT2AKDM4E
	SCHEMBL4590567	0.74	PTPN11 (0.53)	MEN1ALDH1A1KMT2AKDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.