Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31947 | 0.89 | LMNA (0.44) | LMNASMN1; SMN2GAAKMT2AALDH1A1 | |
| SCHEMBL9165337 | 0.84 | LMNA (0.54) | LMNASMN1; SMN2GAAKMT2AALDH1A1 | |
| SCHEMBL9819563 | 0.81 | ALDH1A1 (0.49) | LMNAGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL12636166 | 0.76 | KMT2A (0.52) | MRGPRX4LMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL31944 | 0.75 | PPARA (0.47) | MAPT | |
| SCHEMBL31929 | 0.74 | PDE4A (0.44) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL6101068 | 0.74 | GAA (0.73) | SMN1; SMN2GAAKMT2AALDH1A1MEN1 | |
| SCHEMBL6866159 | 0.73 | CFD (0.70) | MRGPRX4GAACFDALDH1A1KDM4E | |
| SCHEMBL20189519 | 0.72 | RAB9A (0.53) | LMNASMN1; SMN2GAAKMT2ACYP4A11 | |
| SCHEMBL12837926 | 0.72 | MRGPRX4 (0.57) | MRGPRX4GAACYP4F2CYP4A11CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026495-A1 | NOVEL HYDANTOIN DERIVATIVE AND MEDICINAL AGENT COMPRISING SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |