Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31703 | 0.89 | MRGPRX4 (0.47) | LMNASMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL9165337 | 0.83 | LMNA (0.54) | LMNASMN1; SMN2GAAALDH1A1KMT2A | |
| SCHEMBL9819563 | 0.80 | ALDH1A1 (0.49) | LMNAGAAALDH1A1KDM4EKMT2A | |
| SCHEMBL20189519 | 0.79 | RAB9A (0.53) | LMNASMN1; SMN2GAAKDM4EKMT2A | |
| SCHEMBL31773 | 0.78 | LOXL2 (0.52) | LMNASMN1; SMN2ALDH1A1KDM4EMAPK10 | |
| SCHEMBL12634546 | 0.77 | HTT (0.46) | LMNAHPGDSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL31944 | 0.77 | PPARA (0.47) | MAPT | |
| SCHEMBL31929 | 0.75 | PDE4A (0.44) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL23292500 | 0.74 | HPGD (0.54) | LMNAHPGDSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL14415935 | 0.74 | HPGD (0.57) | LMNAHPGDSMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026495-A1 | NOVEL HYDANTOIN DERIVATIVE AND MEDICINAL AGENT COMPRISING SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |