Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | FOS | P01100 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165337 | 0.87 | LMNA (0.54) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL31703 | 0.81 | MRGPRX4 (0.47) | ALDH1A1KDM4EMAPTGAAMEN1 | |
| SCHEMBL31947 | 0.80 | LMNA (0.44) | ALDH1A1KDM4EMAPTTSHRGAA | |
| SCHEMBL6101068 | 0.77 | GAA (0.73) | ALDH1A1KDM4EMAPTGAAMEN1 | |
| SCHEMBL28757730 | 0.75 | EPHX2 (0.47) | ALDH1A1TSHRGAANFKB1CYP1A2 | |
| SCHEMBL5365117 | 0.74 | OPRK1 (0.64) | SHBG | |
| SCHEMBL30065107 | 0.73 | EPHX2 (0.47) | TAAR1MAPTMEN1CYP2C9KMT2A | |
| SCHEMBL20189519 | 0.72 | RAB9A (0.53) | KDM4EHTTGAAMEN1KMT2A | |
| SCHEMBL10639960 | 0.72 | SHBG (0.46) | ALDH1A1TAAR1KDM4EMAPTHTT | |
| SCHEMBL8009140 | 0.71 | EPHX2 (0.47) | ALDH1A1MAPTTSHRGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266117-B1 | PROCESS FOR PURIFIED AMINO ACIDS | MERCK & CO. INC. (US) | 1991-05-02 | — | — | EP | disclosed |
| EP-0257920-B1 | PROCESS FOR L-DOPA | MERCK & CO. INC. (US) | 1990-10-31 | — | — | EP | disclosed |
| EP-0266117-A1 | Process for purified amino acids | MERCK & CO. INC. (US) | 1988-05-04 | — | — | EP | disclosed |
| US-4740615-A | LOW PRESSURE TEMPERATURE GRADIENT CHROMATOGRAPHY | MERCK & CO., INC. (US) | 1988-04-26 | — | — | US | disclosed |
| EP-0257920-A1 | Process for L-dopa | MERCK & CO. INC. (US) | 1988-03-02 | — | — | EP | disclosed |
| US-4716246-A | Process for L-dopa | MERCK & CO., INC. (US) | 1987-12-29 | — | — | US | disclosed |