Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1169137 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TDP1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL7784530 | 0.80 | ALDH1A1 (0.47) | ALDH1A1TDP1SMN1; SMN2PKMATM | |
| SCHEMBL16906258 | 0.77 | APLNR (0.58) | ALDH1A1TDP1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL13732627 | 0.77 | ALDH1A1 (0.40) | ALDH1A1TDP1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL1965844 | 0.76 | — | — | |
| SCHEMBL28604705 | 0.74 | LMNA (0.48) | ALDH1A1TDP1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL10567351 | 0.73 | HSP90AA1 (0.55) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL10566600 | 0.73 | SMN1; SMN2 (0.38) | ALDH1A1TDP1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL29039515 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TDP1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL7799117 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434623-B1 | Cationic azo dyes | CIBA GEIGY AG (CH) | 1995-03-15 | — | — | EP | claimed |