Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL522710 | 0.83 | PIN1 (0.62) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL918351 | 0.83 | HDAC3 (0.56) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL917824 | 0.83 | SMN1; SMN2 (0.64) | POLBKDM4EPKMMEN1KMT2A | |
| SCHEMBL918146 | 0.83 | SMN1; SMN2 (0.64) | POLBKDM4EPKMMEN1KMT2A | |
| SCHEMBL4231048 | 0.82 | SMN1; SMN2 (0.62) | ALDH1A1POLBKDM4EPKMMEN1 | |
| SCHEMBL13202079 | 0.82 | ACHE (0.57) | POLB | |
| SCHEMBL8095237 | 0.82 | ACHE (0.57) | POLB | |
| SCHEMBL1573660 | 0.82 | ACHE (0.57) | POLB | |
| SCHEMBL18954535 | 0.81 | CASP1 (0.52) | ALDH1A1POLBKDM4EMAPTMEN1 | |
| SCHEMBL3860903 | 0.81 | FTO (0.48) | ALDH1A1POLBKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110003878-A1 | NOVEL DERIVATIVES OF PHTHALIMIDE AS HISTONE DEACETYLASE INHIBITORS | UNIVERSIDAD DE GRANADA (ES) | 2011-01-06 | — | — | US | disclosed |
| EP-2045239-A1 | NOVEL DERIVATIVES OF PHTHALIMIDE AS HISTONE DEACETYLASE INHIBITORS | Universidad De Granada (ES) | 2009-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003878-A1 | NOVEL DERIVATIVES OF PHTHALIMIDE AS HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC2, HDAC11 | ALDH1A1 340/4885POLB 624/4885KDM4E 134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.