SCHEMBL916740

SCHEMBL916740

CC(C)(C)c1ccc(SSc2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.52
LMNA P02545 1/20 0.50
TYR P14679 1/20 0.50
ALDH1A1 P00352 7/20 0.47
SMN1; SMN2 Q16637 2/20 0.42
KIF11 P52732 2/20 0.42
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
MAPT P10636 3/20 0.39
HPGD P15428 3/20 0.39
MAPK1 P28482 1/20 0.39
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
PKM P14618 1/20 0.39
RECQL P46063 1/20 0.39
KMT2A Q03164 1/20 0.39
HDAC1 Q13547 1/20 0.39
SLC22A2 O15244 1/20 0.39
SLC22A1 O15245 1/20 0.39
SLC22A3 O75751 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4268940 0.89 TSHR (0.48) TSHRLMNATYRALDH1A1SMN1; SMN2
SCHEMBL11214660 0.89 TSHR (0.48) TSHRLMNATYRALDH1A1SMN1; SMN2
SCHEMBL19540477 0.88 TSHR (0.42) TSHRLMNATYRALDH1A1SMN1; SMN2
SCHEMBL11388046 0.85 TSHR (0.44) TSHRLMNATYRALDH1A1SMN1; SMN2
SCHEMBL25450061 0.84 CYP2D6 (0.41) TSHRLMNATYRALDH1A1SMN1; SMN2
SCHEMBL2271509 0.82 TSHR (0.52) TSHRLMNATYRALDH1A1SMN1; SMN2
SCHEMBL25449464 0.81 ALDH1A1 (0.40) TSHRLMNATYRALDH1A1SMN1; SMN2
SCHEMBL424728 0.80 TSHR (0.73) TSHRLMNATYRALDH1A1KIF11
SCHEMBL10013103 0.80 TSHR (0.50) TSHRLMNATYRALDH1A1SMN1; SMN2
SCHEMBL799910 0.80 EPHX2 (0.53) TSHRLMNATYRALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 314 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0278257-B1 4-TERT.-BUTYL-1,2-BENZENEDITHIOL, COMPLEX COMPOUNDS DERIVED THEREFROM, AND A METHOD OF PRODUCING THE SAME SEITETSU KAGAKU CO., LTD. (JP) 1992-05-13 EP claimed
EP-0278257-A1 4-Tert.-butyl-1,2-benzenedithiol, complex compounds derived therefrom, and a method of producing the same SEITETSU KAGAKU CO., LTD. (JP) 1988-08-17 EP claimed
JP-1125386-A None JP disclosed
JP-63307853-A None JP disclosed
US-12600837-B2 Rubber composition and crosslinked rubber molded product SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-04-14 US disclosed
EP-4527473-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2026-03-25 EP disclosed
US-12544628-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-02-10 US disclosed
US-20260027422-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-01-29 US disclosed
US-20250269241-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2025-08-28 US disclosed
US-12357881-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2025-07-15 US disclosed
EP-4286020-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2025-07-02 EP disclosed
JP-S63307853-A NOVEL 4-TERTIARY BUTYL-1,2-BENZENEDITHIOL, NICKEL COMPLEX THEREOF AND PRODUCTION THEREOF SEITETSU KAGAKU CO LTD 1988-12-15 JP disclosed
EP-0278257-A1 4-Tert.-butyl-1,2-benzenedithiol, complex compounds derived therefrom, and a method of producing the same SEITETSU KAGAKU CO., LTD. (JP) 1988-08-17 EP disclosed
EP-0278257-A1 4-Tert.-butyl-1,2-benzenedithiol, complex compounds derived therefrom, and a method of producing the same SEITETSU KAGAKU CO., LTD. (JP) 1988-08-17 EP disclosed
EP-0043788-B1 IMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL COMPOSITIONS SCHERING AKTIENGESELLSCHAFT (DE) 1985-10-30 EP disclosed
EP-0038459-B1 PROCESS FOR THE PREVENTION OF REVERSION DURING THE MANUFACTURE OF RUBBER VULCANISATES BAYER AG (DE) 1985-07-10 EP disclosed
US-4528298-A Antiinflammatory imidazole derivatives SCHERING AKTIENGESELLSCHAFT (DE) 1985-07-09 US disclosed
US-4402960-A Antiinflammatory imidazole derivatives SCHERING AKTIENGESELLSCHAFT (DE) 1983-09-06 US disclosed
US-4340695-A Vulcanization system, rubber mixture containing said system and a process of vulcanization BAYER AKTIENGESELLSCHAFT (DE) 1982-07-20 US disclosed
US-4303765-A PEPTIZATION WITH AROMATIC POLYSULFIDE BAYER AKTIENGESELLSCHAFT (DE) 1981-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260027422-A1 GOLF BALL KIF5A, KIF5C, SURF4 TSHR 1398/4885LMNA 2773/4885TYR 4020/4885
US-12544628-B2 Golf ball KIF5A, KIF5C, SURF4 TSHR 1538/4885LMNA 2851/4885TYR 3783/4885
US-12600837-B2 Rubber composition and crosslinked rubber molded product RER1, RIF1, SHC1 TSHR 2922/4885LMNA 2803/4885TYR 3442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.