Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.47 |
| ▸ | IDH2 | P48735 | 2/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | KCNK18 | Q7Z418 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24206408 | 0.87 | IDH2 (0.49) | KIF11IDH2ABCG2GRM4KCNK18 | |
| SCHEMBL30365006 | 0.84 | KIF11 (0.56) | KIF11IDH2ABCG2GRM4KCNK18 | |
| SCHEMBL21252630 | 0.84 | KIF11 (0.56) | KIF11IDH2ABCG2GRM4KCNK18 | |
| SCHEMBL21625856 | 0.84 | KIF11 (0.54) | KIF11IDH2ABCG2GRM4KCNK18 | |
| SCHEMBL29514710 | 0.84 | KIF11 (0.54) | KIF11IDH2ABCG2GRM4KCNK18 | |
| SCHEMBL915691 | 0.82 | NR1H2 (0.44) | KIF11ABCG2MAPTSMN1; SMN2 | |
| SCHEMBL3398439 | 0.82 | ALDH1A1 (0.60) | KIF11IDH2ABCG2GRM4KCNK18 | |
| SCHEMBL26316048 | 0.79 | P2RX1 (0.50) | KIF11ABCG2GRM4KCNK18BRD4 | |
| SCHEMBL12266446 | 0.79 | MAPT (0.53) | KIF11ABCG2GRM4KCNK18BRD4 | |
| SCHEMBL22225354 | 0.78 | KIF11 (0.50) | KIF11IDH2ABCG2GRM4KCNK18 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8647754-B2 | Aromatic diamine derivative and organic electroluminescent device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| US-20110006289-A1 | AROMATIC DIAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110006289-A1 | AROMATIC DIAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | AOC1, DDC, CCNL2 | KIF11 1337/4885IDH2 1223/4885ABCG2 3312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.