SCHEMBL915691

SCHEMBL915691

CC(C)(C)c1ccc(Nc2ccc([Si](C)(C)C)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.44
NR1H3 Q13133 1/20 0.44
DHODH Q02127 2/20 0.41
PTGIR P43119 1/20 0.40
ABCG2 Q9UNQ0 1/20 0.40
PDK1 Q15118 1/20 0.40
PDK2 Q15119 1/20 0.40
PDK3 Q15120 1/20 0.40
PDK4 Q16654 1/20 0.40
TRPV1 Q8NER1 1/20 0.40
TSHR P16473 1/20 0.39
CSNK1D P48730 3/20 0.39
CSNK1G2 P78368 3/20 0.39
LMNA P02545 1/20 0.38
TYR P14679 1/20 0.38
KIF11 P52732 2/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
MAPT P10636 1/20 0.38
XBP1 P17861 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10128978 0.89 CYP1A2 (0.42) NR1H2NR1H3TRPV1TSHRLMNA
SCHEMBL12688243 0.87 NR1H2 (0.54) NR1H2NR1H3TSHRLMNATYR
SCHEMBL2392625 0.84 TSHR (0.52) DHODHPTGIRABCG2PDK1PDK2
SCHEMBL2270398 0.84 ALDH1A1 (0.43) NR1H2NR1H3TSHRLMNAMEN1
SCHEMBL49741 0.84 TSHR (0.52) DHODHPTGIRABCG2PDK1PDK2
SCHEMBL916746 0.82 KIF11 (0.47) ABCG2KIF11MAPTSMN1; SMN2
SCHEMBL19735232 0.80 KIF11 (0.58) NR1H2NR1H3TSHRLMNATYR
SCHEMBL13321302 0.78 KIF11 (0.57) DHODHABCG2TSHRLMNATYR
SCHEMBL22432523 0.78 TSHR (0.46) DHODHPTGIRPDK1PDK2PDK3
SCHEMBL5396983 0.78 TSHR (0.46) DHODHPDK1PDK2PDK3PDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3255692-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2023-07-05 EP disclosed
US-11683980-B2 Condensed fluorene derivative comprising heterocyclic ring SFC CO., LTD. (KR) 2023-06-20 US disclosed
US-11683980-B2 Condensed fluorene derivative comprising heterocyclic ring SFC CO., LTD. (KR) 2023-06-20 US disclosed
US-11672172-B2 Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same SFC CO., LTD. (KR) 2023-06-06 US disclosed
US-11672172-B2 Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same SFC CO., LTD. (KR) 2023-06-06 US disclosed
EP-4116297-A1 CONDENSED FLUORENE DERIVATIVE COMPRISING HETEROCYCLIC RING SFC Co., Ltd. (KR) 2023-01-11 EP disclosed
US-11532792-B2 Organic light emitting diode having high efficiency SFC CO., LTD. (KR) 2022-12-20 US disclosed
EP-3229284-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-08-31 EP disclosed
EP-3223330-B1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2022-02-23 EP disclosed
US-20220017544-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2022-01-20 US disclosed
EP-1437395-B1 Organic electroluminescent device LG DISPLAY CO LTD (KR) 2011-12-14 EP disclosed
US-20110006289-A1 AROMATIC DIAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2011-01-13 US disclosed
US-20100155714-A1 ORGANIC ELECTROLUMINESCENT DEVICE LG DISPLAY CO., LTD. (KR) 2010-06-24 US disclosed
US-20100155714-A1 ORGANIC ELECTROLUMINESCENT DEVICE LG DISPLAY CO., LTD. (KR) 2010-06-24 US disclosed
US-7700201-B2 Organic electroluminescent device LG DISPLAY CO., LTD. (KR) 2010-04-20 US disclosed
US-7700201-B2 Organic electroluminescent device LG DISPLAY CO., LTD. (KR) 2010-04-20 US disclosed
CN-100481574-C Organic electro luminous device LG DISPLAY CO LTD (KR) 2009-04-22 CN disclosed
CN-1535089-A Organic electro luminous device LG������ʽ���� 2004-10-06 CN disclosed
US-20040137270-A1 Organic electroluminescent device LG ELECTRONICS INC. 2004-07-15 US disclosed
EP-1437395-A2 Organic electroluminescent device LG ELECTRONICS INC. (KR) 2004-07-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11532792-B2 Organic light emitting diode having high efficiency CYBA, SLC1A2, MAOB NR1H2 1285/4885NR1H3 902/4885DHODH 502/4885
US-11683980-B2 Condensed fluorene derivative comprising heterocyclic ring CCNE2, INF2, AFF4 NR1H2 1635/4885NR1H3 1871/4885DHODH 1726/4885
US-20100155714-A1 ORGANIC ELECTROLUMINESCENT DEVICE L1CAM, AOC2, AOC1 NR1H2 3731/4885NR1H3 3367/4885DHODH 3085/4885
US-20220017544-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME NR2E3, CBR3, CBR1 NR1H2 6/4885NR1H3 9/4885DHODH 3877/4885
US-20110006289-A1 AROMATIC DIAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME AOC1, DDC, CCNL2 NR1H2 1958/4885NR1H3 2040/4885DHODH 869/4885
US-11672172-B2 Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same DDC, TYR, AOC2 NR1H2 1648/4885NR1H3 1499/4885DHODH 176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.