Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175954 | 0.78 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL9168133 | 0.77 | PTPN1 (0.46) | ALDH1A1PTPN1L3MBTL1MEN1KMT2A | |
| SCHEMBL9173922 | 0.77 | PTPN1 (0.43) | ALDH1A1PTPN1L3MBTL1MEN1KMT2A | |
| SCHEMBL4547729 | 0.71 | ALDH1A1 (0.52) | ALDH1A1BRD4CYP2A6KIF11 | |
| SCHEMBL5793081 | 0.71 | CYP11B2 (0.44) | ALDH1A1KMT2ACYP2A6 | |
| SCHEMBL15391081 | 0.70 | L3MBTL1 (0.50) | ALDH1A1PTPN1L3MBTL1MEN1KMT2A | |
| SCHEMBL17011033 | 0.70 | L3MBTL1 (0.50) | ALDH1A1PTPN1L3MBTL1MEN1KMT2A | |
| SCHEMBL16381821 | 0.68 | ALDH1A1 (0.54) | ALDH1A1BRD4MEN1KMT2ACYP2A6 | |
| SCHEMBL5793083 | 0.68 | MIF (0.48) | ALDH1A1L3MBTL1MEN1KMT2AHSP90AA1 | |
| SCHEMBL9176674 | 0.68 | TNKS (0.40) | ALDH1A1PTPN1BRD4CYP2A6EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640080-A1 | SUBSTITUTED INDOLES AND AZAINDOLES AS ANGIOTENSIN II ANTAGONISTS. | SYNTEX INC (US) | 1995-03-01 | — | — | EP | disclosed |
| US-5380739-A | Angiotensin II antagonists | SYNTEX (U.S.A.) INC. (US) | 1995-01-10 | — | — | US | disclosed |
| WO-1993023391-A1 | SUBSTITUTED INDOLES AND AZAINDOLES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-11-25 | — | — | WO | disclosed |