⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanazole SCHEMBL6030091 | 0.74 | ALDH1A1 (0.36) | — | |
| SCHEMBL9098171 | 0.68 | ADORA3 (0.50) | — | |
| Hydrochloric Acid SCHEMBL28247161 | 0.67 | — | — | |
| SCHEMBL27976239 | 0.65 | TSHR (0.33) | — | |
| SCHEMBL9395961 | 0.65 | CYP1A2 (0.36) | — | |
| SCHEMBL3634528 | 0.65 | CA5A (0.36) | — | |
| SCHEMBL8627156 | 0.62 | KDM4E (0.39) | — | |
| SCHEMBL3463283 | 0.61 | GAA (0.37) | — | |
| Guanazole SCHEMBL31753920 | 0.59 | — | — | |
| Sulfuric Acid SCHEMBL3344978 | 0.57 | CA5A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375061-B1 | Preparation of 5-amino-1,2,4-triazole-3-sulfonamides and intermediates | DOWELANCO (US) | 1995-04-19 | — | — | EP | disclosed |
| US-5382674-A | Preparation of 5-amino-1,2,4-triazole-3-sulfonamides | DOWELANCO (US) | 1995-01-17 | — | — | US | disclosed |
| US-5359079-A | 5-amino-1,2,4-triazole-3-sulfonamides | DOWELANCO (US) | 1994-10-25 | — | — | US | disclosed |
| EP-0401907-B1 | Preparation of N-(3-(((aryl)amino)sulfonyl)-1H-1,2,4-triazol-5-yl)amines | DOWELANCO (US) | 1994-09-28 | — | — | EP | disclosed |
| EP-0401907-A1 | Preparation of N-(3-(((aryl)amino)sulfonyl)-1H-1,2,4-triazol-5-yl)amines | DOWELANCO (US) | 1990-12-12 | — | — | EP | disclosed |
| EP-0375061-A1 | Preparation of 5-amino-1,2,4-triazole-3-sulfonamides and intermediates | DowElanco (US) | 1990-06-27 | — | — | EP | disclosed |
| US-4937350-A | Preparation of N-(-3(((aryl)amino)suldonyl)-1H-1,2,4-triazol-5-yl)amines | THE DOW CHEMICAL COMPANY (US) | 1990-06-26 | — | — | US | disclosed |
| EP-0272628-A2 | 6,7-Dihydro-[1,2,4]triazolo[1,5-a][1,3,5]triazine-2-sulfonamides, process for their preparation and their use as agents with a herbicidal and growth-regulating activity | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-06-29 | — | — | EP | disclosed |