Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9168939 | 0.95 | SIGMAR1 (0.30) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8674390 | 0.85 | — | — | |
| SCHEMBL6672404 | 0.82 | SIGMAR1 (0.31) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8674387 | 0.80 | — | — | |
| SCHEMBL9779213 | 0.78 | SIGMAR1 (0.36) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL570892 | 0.77 | MEN1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL9164387 | 0.76 | — | — | |
| SCHEMBL6674779 | 0.76 | HTR6 (0.30) | — | |
| Hydrochloric Acid SCHEMBL6557718 | 0.75 | MEN1 (0.40) | — | |
| SCHEMBL8584988 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420320-A | Method for preparing cyclopentadienyl-type ligands and metallocene compounds | PHILLIPS PETROLEUM COMPANY (US) | 1995-05-30 | — | — | US | disclosed |