Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL524858 | 0.79 | GPR3 (0.33) | — | |
| Fluoride Ion SCHEMBL1130995 | 0.79 | GPR3 (0.33) | — | |
| Methane SCHEMBL5348855 | 0.78 | GPR3 (0.32) | — | |
| Cyclopentane SCHEMBL6557619 | 0.77 | BCHE (0.33) | — | |
| Hydrochloric Acid SCHEMBL9168946 | 0.77 | SIGMAR1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL7180983 | 0.76 | GPR3 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7621841 | 0.76 | GPR3 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7168371 | 0.75 | CHRNB2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL9168939 | 0.74 | SIGMAR1 (0.30) | — | |
| SCHEMBL9779213 | 0.74 | SIGMAR1 (0.36) | MEN1POLBKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601225-B1 | SHEAR-STABLE HIGH VISCOSITY POLYALPHAOLEFINS | EXXONMOBIL CHEM PATENTS INC (US) | 2015-11-04 | — | — | EP | disclosed |
| US-20130210996-A1 | Shear-Stable High Viscosity Polyalphaolefins | ExxonMobil Chemical Company - Law Technology (US) | 2013-08-15 | — | — | US | disclosed |
| EP-2601225-A2 | SHEAR-STABLE HIGH VISCOSITY POLYALPHAOLEFINS | ExxonMobil Chemical Patents Inc. (US) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012018463-A2 | SHEAR-STABLE HIGH VISCOSITY POLYALPHAOLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-02-09 | — | — | WO | disclosed |