Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91827 | 0.89 | LMNA (0.34) | MAPTCYP1A2CYP2C19SLC6A2P2RY14 | |
| SCHEMBL91736 | 0.86 | MAPT (0.39) | MAPTCYP1A2CYP2C19DHODHTDP1 | |
| SCHEMBL91791 | 0.85 | KIF11 (0.35) | MAPTCYP1A2CYP2C19SLC6A2P2RY14 | |
| SCHEMBL91751 | 0.82 | KMT2A (0.35) | MAPTCYP1A2CYP2C19TDP1POLB | |
| SCHEMBL91739 | 0.80 | FFAR4 (0.31) | — | |
| SCHEMBL91705 | 0.79 | MAPT (0.41) | MAPTCYP1A2CYP2C19TDP1 | |
| SCHEMBL91740 | 0.79 | MAPT (0.36) | MAPTCYP1A2CYP2C19TDP1POLB | |
| SCHEMBL91715 | 0.79 | SLC6A2 (0.32) | SLC6A2P2RY14 | |
| SCHEMBL91719 | 0.76 | CYP1A2 (0.33) | MAPTCYP1A2CYP2C19DHODHPOLB | |
| SCHEMBL91716 | 0.75 | MAPT (0.34) | MAPTCYP1A2CYP2C19POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |